Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still’s disease - Jia, Jinchao; Wang, Mengyan; Ma, Yuning; Meng, Jianfen; Zhu, Dehao; Chen, Xia; Shi, Hui; Sun, Yue; Liu, Honglei; Cheng, Xiaobing; Su, Yutong; Ye, Junna; et al. (BMC medicine, 2023)
Keywords: Adult-onset Still’s disease; Analysis; Antibodies; Arthritis; Biomarkers; CD16 antigen; CD163 antigen; CD80 antigen; CD86 antigen; Cell activation; Chemokines; Coronaviruses; COVID-19; CXCL10; CXCL10 protein; Cytokine storm; Cytokines; Deoxyribonuclease; Deoxyribonucleic acid; Disease; DNA; DNA sensing; Enzyme-linked immunosorbent assay; Fever; Flow cytometry; Gene expression; Gene sequencing; Health aspects; Immune system; Inflammasomes; Inflammation; Inflammatory diseases; Innate immunity; Leukocytes (neutrophilic); Lymphocytes; Macrophages; Measurement; Monocyte subset; Monocytes; mRNA; Neutrophil extracellular traps; Neutrophils; Pathogenesis; Phagocytes; Phagocytosis; Regulatory mechanisms (biology); Ribonucleic acid; RNA; RNA sequencing; Therapeutic targets; Tumor necrosis factor-TNF; China; United States--US; Japan; CXCL10; Monocyte subset; Adult-onset Still’s disease; DNA sensing; Neutrophil extracellular traps