Genomic alterations related to HPV infection status in a cohort of Chinese prostate cancer patients

• Published in: European journal of medical research Vol. 28; no. 1; pp. 239 - 10
• Main Authors: Lang, Bin, Cao, Chen, Zhao, Xiaoxiao, Wang, Yi, Cao, Ying, Zhou, Xueying, Zhao, Tong, Wang, Yuyan, Liu, Ting, Liang, Wenjia, Hu, Zheng, Tian, Xun, Zhang, Jingjing, Yan, Yongji
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.07.2023; BioMed Central; BMC
• Subjects: Age groups; Cancer patients; Capture sequencing; Care and treatment; Development and progression; East Asian People; Genetic aspects; Genomes; Genomics; Genotype; Human papillomavirus; Humans; Infection; Infections; Male; Medical screening; Mutation; Nuclear Proteins - genetics; Papillomavirus infections; Papillomavirus Infections - complications; Papillomavirus Infections - genetics; Prostate cancer; Prostatic Neoplasms - complications; Prostatic Neoplasms - genetics; Prostatic Neoplasms - pathology; Repressor Proteins - genetics; Sexually transmitted diseases; Tumors; Whole-exome sequencing; Xeroderma Pigmentosum Group D Protein - genetics; China; Human papillomavirus; Capture sequencing; Prostate cancer; Whole-exome sequencing

Human papillomavirus (HPV) has been proposed as a potential pathogenetic organism involved in prostate cancer (PCa), but the association between HPV infection and relevant genomic changes in PCa is poorly understood. To evaluate the relationship between HPV genotypes and genomic alterations in PCa,...