Future atherosclerotic cardiovascular disease in systemic lupus erythematosus based on CSTAR (XXVIII): the effect of different antiphospholipid antibodies isotypes

• Published in: BMC medicine Vol. 23; no. 1; pp. 8 - 13
• Main Authors: Huang, Can, Ding, Yufang, Chen, Zhen, Wu, Lijun, Wei, Wei, Zhao, Cheng, Yang, Min, Lin, Shudian, Wang, Qian, Tian, Xinping, Zhao, Jiuliang, Li, Mengtao, Zeng, Xiaofeng
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.01.2025; BioMed Central; BMC
• Subjects: Adult; Antibodies; Antibodies, Antiphospholipid - blood; Anticoagulants; Antiphospholipid antibodies; Antiphospholipid antibodies (aPLs); Antiphospholipid syndrome (APS); Arteriosclerosis; Arthritis; Aspirin; Asymptomatic; Atherosclerosis; Atherosclerosis - blood; Atherosclerosis - complications; Atherosclerosis - epidemiology; Atherosclerosis - immunology; Atherosclerotic cardiovascular disease (ASCVD); Autoimmune diseases; Body mass index; Cardiolipin; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - immunology; Care and treatment; Cerebral infarction; China - epidemiology; Chronic conditions; Confounding (Statistics); Diabetes; Diagnosis; Female; Glycoprotein I; Glycoproteins; Health risks; Heart attacks; Humans; Hyperlipidemia; Hypertension; Immunoglobulin G; Immunoglobulin Isotypes - blood; Immunoglobulin M; Isotypes; Lupus; Lupus Erythematosus, Systemic - blood; Lupus Erythematosus, Systemic - complications; Lupus Erythematosus, Systemic - epidemiology; Lupus Erythematosus, Systemic - immunology; Male; Medical imaging; Medical prognosis; Middle Aged; Myocardial infarction; Patients; Prevention; Prospective Studies; Quality control; Regression analysis; Review boards; Risk Factors; Systemic lupus erythematosus; Systemic lupus erythematosus (SLE); Testing; Thrombosis; China; Germany; Antiphospholipid syndrome (APS); Aspirin; Antiphospholipid antibodies (aPLs); Systemic lupus erythematosus (SLE); Atherosclerotic cardiovascular disease (ASCVD)

Patients with systemic lupus erythematosus (SLE) suffered from an increasing risk of cardiovascular diseases. In this multi-center prospective study, we aimed to determine the association between antiphospholipid antibodies (aPLs) and future atherosclerotic cardiovascular disease (ASCVD) in SLE. In...