Deubiquitinating Function of Ataxin-3: Insights from the Solution Structure of the Josephin Domain - Mao, Yuxin; Senic-Matuglia, Francesca; Di Fiore, Pier Paolo; Polo, Simona; Hodsdon, Michael E.; De Camilli, Pietro (Proceedings of the National Academy of Sciences - PNAS, 2005)
Keywords: Active sites; Ataxin-3; Biological Sciences; Catalysis; Catalytic activity; Chemical equilibrium; Enzymes; Humans; Machado Joseph disease; Models, Molecular; Mutation; Nerve Tissue Proteins - chemistry; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Neurodegenerative diseases; Neurological disorders; NMR; Nuclear magnetic resonance; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Proteins; Repressor Proteins; Structural analysis; Ubiquitin - metabolism; Ubiquitins; Western blotting