Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway - Zhang, Jingyuan; Yang, Siyun; Chen, Xiaodong; Zhang, Fanqin; Guo, Siyu; Wu, Chao; Wang, Tieshan; Wang, Haojia; Lu, Shan; Qiao, Chuanqi; Sheng, Xiaoguang; Liu, Shuqi; et al. (Chinese medicine, 2025)
Keywords: 1-Phosphatidylinositol 3-kinase; Adenocarcinoma; Aidi injection; AKT protein; Antibodies; Apoptosis; Bioinformatics; Biotechnology; Cancer cells; Cancer therapies; Cell cycle; Cell growth; Cell proliferation; Cellular signal transduction; Combination therapy; Dosage and administration; Drug resistance; Drug therapy; Focal adhesion kinase; Gefitinib; Gefitinib resistance; Health aspects; Injection; Lung cancer; Medical research; Medicine, Chinese; Molecular modelling; Mutation; Non-small cell lung cancer; Non-small cell lung carcinoma; Pancreatic cancer; Pharmacology, Experimental; Physiological aspects; PLAT/FAK/AKT pathway; Proteases; Protein kinases; Small cell lung carcinoma; Toxicity; Traditional Chinese medicine; Transcriptomes; Tumors; China; Beijing China; Aidi injection; PLAT/FAK/AKT pathway; Non-small cell lung cancer; Gefitinib resistance