Controlling Ligand Substitution Reactions of Organometallic Complexes: Tuning Cancer Cell Cytotoxicity - Wang, Fuyi; Abraha Habtemariam; Erwin P. L. van der Geer; Fernández, Rafael; Michael Melchart; Robert J. Deeth; Rhona Aird; Sylvie Guichard; Francesca P. A. Fabbiani; Patricia Lozano-Casal; Iain D. H. Oswald; Duncan I. Jodrell; et al. (Proceedings of the National Academy of Sciences - PNAS, 2005)
Keywords: Adducts; Antineoplastic Agents - chemistry; Antineoplastic Agents - toxicity; Antineoplastics; Arene; Benzene; Cancer; Cell Line, Tumor; Cell Survival - drug effects; Chemical reactions; Chemistry; Chlorides; Cytotoxicity; Design; DNA; Drug Design; Female; Guanosine Monophosphate - chemistry; Guanosine Monophosphate - metabolism; Half lives; Halides; Humans; Hydrolysis; Inhibitory Concentration 50; Kinetics; Ligands; Liquid chromatography; Molecular Structure; Organometallic Compounds - chemistry; Organometallic Compounds - toxicity; Ovarian cancer; Ovarian Neoplasms - genetics; Ovarian Neoplasms - pathology; Pharmacology; Physical Sciences; Ruthenium; Ruthenium - chemistry; Ruthenium - toxicity