An autophagy‐related long non‐coding RNA signature for glioma

• Published in: FEBS open bio Vol. 9; no. 4; pp. 653 - 667
• Main Authors: Luan, Fangkun, Chen, Wenjie, Chen, Miao, Yan, Jun, Chen, Hao, Yu, Haiyue, Liu, Tieqi, Mo, Ligen
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.04.2019; John Wiley and Sons Inc; Wiley
• Subjects: Apoptosis; Autophagy; Autophagy - genetics; Cancer therapies; CCGA; Cell death; Central nervous system; China; data collection; Datasets; DNA methylation; DNA microarrays; Female; Gene expression; Gene Expression Regulation, Neoplastic; Gene set enrichment analysis; genes; Genomes; glioma; Glioma - diagnosis; Glioma - genetics; Glioma cells; hazard ratio; Humans; Interleukin 2; interleukins; Janus kinase; long non‐coding RNA; Male; Medical prognosis; microarray technology; MicroRNAs; MicroRNAs - genetics; Nervous system; non-coding RNA; p53 Protein; Phagocytosis; Physiology; Prognosis; prognostic signature; Regression analysis; Ribonucleic acid; Risk groups; RNA; RNA, Long Noncoding - analysis; Signal transduction; Software; Stat5 protein; TCGA; transactivators; Transcription; Tumor necrosis factor-α; tumor necrosis factors; Tumors; China; United States > US; glioma; autophagy; CCGA; TCGA; long non‐coding RNA; prognostic signature

Glioma is one of the most common types of malignant primary central nervous system tumor, and prognosis for this disease is poor. As autophagic drugs have been reported to induce glioma cell death, we investigated the potential prognostic role of autophagy‐associated long non‐coding RNA (lncRNA) in...