Genetic causes of male infertility: snapshot on morphological abnormalities of the sperm flagellum

• Published in: Basic and clinical andrology Vol. 29; no. 1; p. 2
• Main Authors: Nsota Mbango, Jean-Fabrice, Coutton, Charles, Arnoult, Christophe, Ray, Pierre F., Touré, Aminata
• Format: Journal Article
• Language: English
• Published: England BioMed Central 04.03.2019
• Subjects: Defects; Dyskinesia; Genes; Genotype & phenotype; Infertility; Life Sciences; Morphology; Mutation; Parasites; Proteins; Sperm; DNAH; MMAF; WDR; Sperm; Male infertility; Genetic; AK; CFAP

Male infertility due to Multiple Morphological Abnormalities of the sperm Flagella (MMAF), is characterized by nearly total asthenozoospermia due to the presence of a mosaic of sperm flagellar anomalies, which corresponds to short, angulated, absent flagella and flagella of irregular calibre. In the...