Manual and educational therapy in the treatment of hemophilic arthropathy of the elbow: a randomized pilot study

• Published in: Orphanet journal of rare diseases Vol. 13; no. 1; p. 151
• Main Authors: Cuesta-Barriuso, Rubén, Gómez-Conesa, Antonia, López-Pina, José-Antonio
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.09.2018; BioMed Central; BMC
• Subjects: Adult; Arm; Atrophy; Care and treatment; Causes of; Clinical trials; Complications and side effects; Congenital diseases; Elbow; Elbow - pathology; Exercise Therapy - methods; Female; Health aspects; Hemarthrosis; Hemarthrosis - therapy; Hemophilia; Hemophilia A - therapy; Humans; Joint disease; Joint Diseases - therapy; Joint surgery; Male; Manipulative therapy; Medical research; Methods; Middle Aged; Muscles; Orthopedic apparatus; Pain; Patient education; Patients; Physical therapy; Physiotherapy modalities; Pilot Projects; Proprioception; Range of Motion, Articular - physiology; Rare diseases; Young Adult; Physiotherapy modalities; Joint disease; Elbow; Hemophilia
• ISSN: 1750-1172; 1750-1172
• DOI: 10.1186/s13023-018-0884-5

Elbow arthropathy is characteristic in patients with hemophilia. Arthropathy is manifested by decreased range of motion, pain, loss of strength and muscular atrophy, and axial changes. The objective is to evaluate the safety of two physiotherapy programs combining manual therapy and home exercises with educational sessions in patients with hemophilic elbow arthropathy. This is a randomized study with 27 patients with elbow hemophilic arthropathy with a mean age of 34.48 (SD: 12.99) years, were randomised to Manual Therapy group, educational group and control group. The physiotherapy programmes were: manual therapy through joint traction, passive muscles stretching and proprioceptive neuromuscular facilitation; and educational sessions and daily home exercises. The study lasted for twelve weeks, with two sessions a week in manual therapy group and one session every two weeks with daily home exercises in educational group. The variables measured were range of motion of elbow, biceps strength, circumference of arm, and elbow pain. The treatment with manual therapy improved the circumference of arm, flexion elbow and elbow pain. Six months later, MT group still enjoyed improved. In the educational group there were improvements, but not significant, in the measured variables. Neither of the two physiotherapy interventions caused elbow hemarthrosis. The treatment with manual therapy improved the range of movement and circumference of arm, and lessened pain in hemophilic patients with chronic elbow arthropathy. No hemarthrosis was recorded during treatment or during the follow-up period. Larger randomized clinical trials are required to confirm the results of this study. ( NCT02198040 ). Registered 22 July 2014, retrospectively registered.