Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease - Hamza, Taye H; Zabetian, Cyrus P; Tenesa, Albert; Laederach, Alain; Montimurro, Jennifer; Yearout, Dora; Kay, Denise M; Doheny, Kimberly F; Paschall, Justin; Pugh, Elizabeth; Kusel, Victoria I; Collura, Randall; et al. (Nature genetics, 2010)
Keywords: 631/1647/2217/2138; 631/208/727/2000; 692/699/375/365/1718; Adult; Age of Onset; Aged; Aged, 80 and over; Agriculture; Animal Genetics and Genomics; Antiparkinsonian agents; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Cancer Research; Case-Control Studies; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Drug therapy; Female; Fundamental and applied biological sciences. Psychology; Gene Function; Genetic aspects; Genetic Linkage; Genetic Predisposition to Disease; Genetic Variation - physiology; Genetics of eukaryotes. Biological and molecular evolution; Genome-Wide Association Study; Health aspects; Histocompatibility antigens; HLA Antigens - genetics; HLA histocompatibility antigens; Human Genetics; Humans; letter; Male; Medical sciences; Meta-Analysis as Topic; Middle Aged; Nervous system (semeiology, syndromes); Nervous system as a whole; Neurology; Odds Ratio; Parkinson Disease - epidemiology; Parkinson Disease - genetics; Parkinson's disease; Physiological aspects; Risk factors; Single nucleotide polymorphisms; Young Adult; United States; Nervous system diseases; Late; Genetic variability; Sporadic; Genetic variant; Central nervous system disease; Parkinson disease; Degenerative disease; Cerebral disorder; Extrapyramidal syndrome