GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli - Wang, Xiaowei; Li, Qinggang; Sun, Cunmin; Cai, Zhen; Zheng, Xiaomei; Guo, Xuan; Ni, Xiaomeng; Zhou, Wenjuan; Guo, Yanmei; Zheng, Ping; Chen, Ning; Sun, Jibin; et al. (Microbial cell factories, 2019)
Keywords: Adaptive laboratory evolution; Amino acids; Arabinose; Backup software; Biological evolution; Chemicals; Chlorides; Deoxyribonucleic acid; DNA; DNA polymerase; DNA-directed DNA polymerase; E coli; Efficiency; Engineering; Escherichia coli; Evolution; Fermentation; Fermentation broth; Genetic aspects; Genetic research; Genomes; Genomics; Genotypes; Glucose; GREACE; Industrial engineering; Industrial production; Laboratories; Lysine; Lysine production; Manufacturing engineering; Metabolic flux; Metabolism; Metabolites; Metabolomics; Microorganisms; Molecular biology; Monosaccharides; Mutagenesis; Mutants; Mutation; Organic chemistry; Oxidative stress; Potassium; Production capacity; Proofreading; Proteins; Sodium chloride; Beijing China; United States--US; China; Lysine production; GREACE; Fermentation broth; Escherichia coli; Adaptive laboratory evolution