Signature pattern of gene expression and signaling pathway in premature diabetic patients uncover their correlation to early age coronary heart disease

• Published in: Diabetology and metabolic syndrome Vol. 14; no. 1; pp. 107 - 15
• Main Authors: Ahmadloo, Salma, Ling, King-Hwa, Fazli, Ahmad, Larijani, Ghazaleh, Ghodsian, Nooshin, Mohammadi, Sanaz, Amini, Naser, Hosseinpour Sarmadi, Vahid, Ismail, Patimah
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 29.07.2022; BioMed Central; BMC
• Subjects: Age; AKT2 protein; Analysis; Aquaporin 2; Cardiovascular disease; Care and treatment; Coronary artery disease; Coronary heart disease; Development and progression; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes therapy; Diabetics; Fasting; Foxp3 protein; Gender; Gene expression; Genes; Genetic research; Glucose; Glucosephosphate dehydrogenase; Heart; Heart diseases; Interleukin 6; Males; Medical records; Medical research; Medicine, Experimental; Minority & ethnic groups; Risk factors; RNA; Signal transduction; Signaling pathway; Type 2 diabetes; Type 2 diabetes mellitus; Malaysia; Germany; Type 2 diabetes mellitus; Signaling pathway; Gene expression; Coronary heart disease

Coronary Heart Disease (CHD) is the leading cause of death in industrialized countries. There is currently no direct relation between CHD and type 2 diabetes mellitus (T2D), one of the major modifiable risk factors for CHD. This study was carried out for genes expression profiling of T2D associated...