Identification of a potentially functional circRNA–miRNA–mRNA regulatory network for investigating pathogenesis and providing possible biomarkers of bladder cancer

• Published in: Cancer cell international Vol. 20; no. 1; pp. 31 - 15
• Main Authors: Lu, Hong-cheng, Yao, Jia-qi, Yang, Xiao, Han, Jie, Wang, Jing-zi, Xu, Kun, Zhou, Rui, Yu, Hao, Lv, Qiang, Gu, Min
• Format: Journal Article
• Language: English
• Published: England BioMed Central 29.01.2020; BMC
• Subjects: 1-Phosphatidylinositol 3-kinase; AKT protein; Biomarker; Biomarkers; Bladder cancer; Cancer; Cancer therapies; Cell cycle; ceRNA; circRNA; Computer applications; DNA microarrays; Gene expression; Genomes; Identification; MAP kinase; Medical prognosis; MicroRNAs; miRNA; Oncology; Pathogenesis; Polymerase chain reaction; Primary Research; Statistical analysis; Therapeutic applications; United States > US; China; ceRNA; Biomarker; circRNA; Bladder cancer

Circular RNAs (circRNAs) have received considerable attention in human cancer research. However, many circRNAs remain to be detected. In our study, we determined novel circRNAs and investigated their effects on bladder cancer (BCa). Microarray dataset GSE92675 was downloaded from Gene Expression Omn...