Gut microbiota-mediated immunomodulation in tumor

• Published in: Journal of experimental & clinical cancer research Vol. 40; no. 1; pp. 221 - 20
• Main Authors: Liu, Xinyi, Chen, Yanjie, Zhang, Si, Dong, Ling
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.07.2021; BioMed Central; BMC
• Subjects: Adaptive immunity; Analysis; Antibiotics; Antigen presentation; B cells; Cancer; Cytokines; Cytotoxicity; Development and progression; Gastrointestinal Microbiome - drug effects; Gastrointestinal system; Gene expression; Gut microbiota; Health aspects; Humans; Immune checkpoint inhibitor; Immune checkpoint inhibitors; Immunomodulation - immunology; Immunotherapy; Lymphocytes; Medical prognosis; Microbiota; Microbiota (Symbiotic organisms); Neoplasms - drug therapy; Neutrophils; Pathogenesis; Peptides; Physiological aspects; Review; T cell receptors; Tumor immunity; Tumors; Gut microbiota; Tumor immunity; Antibiotics; Immune checkpoint inhibitor

Tumor immunity consists of various types of cells, which serve an important role in antitumor therapy. The gastrointestinal tract is colonized by trillions of microorganisms, which form the gut microbiota. In addition to pathogen defense and maintaining the intestinal ecosystem, gut microbiota also...