On the utilization of the induced pluripotent stem cell (iPSC) model to study substance use disorders: A scoping review protocol

• Published in: PloS one Vol. 18; no. 10; p. e0292238
• Main Authors: Niemis, Wasiri, Peterson, Shenita R, Javier, Chrisabella, Nguyen, Amy, Subiah, Sanchi, Palmer, Rohan H C
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 12.10.2023; Public Library of Science (PLoS)
• Subjects: Addictions; Alcohol use; Amphetamines; Analysis; Behavior, Addictive; Biology and Life Sciences; Care and treatment; Clinical trials; Cocaine; Disease; Disorders; Drug abuse; Drug addiction; Drug overdose; Drug use; Electronic cigarettes; Fibroblasts; Health aspects; Humans; Induced Pluripotent Stem Cells; Literature reviews; Marijuana; Medical care; Medical research; Medicine and Health Sciences; Medicine, Experimental; Mental disorders; Meta-Analysis as Topic; Narcotics; Patient outcomes; Pluripotency; Population; Research and Analysis Methods; Research Design; Review Literature as Topic; Reviews; Social Sciences; Somatic cells; Stem cells; Study Protocol; Substance abuse; Substance use; Substance use disorder; Substance-Related Disorders; Systematic Reviews as Topic; Tobacco; Transcription factors; Trends; Utilization; United States; Australia; United Kingdom; United States > US

Induced pluripotent stem cells (iPSCs) are cells derived from somatic cells via reprogramming techniques. The iPSC approach has been increasingly used in neuropsychiatric research in the last decade. Though substance use disorders (SUDs) are a commonly occurring psychiatric disorder, the application...