Phylogeny-wide conservation and change in developmental expression, cell-type specificity and functional domains of the transcriptional regulators of social amoebas

• Published in: BMC genomics Vol. 20; no. 1; pp. 890 - 13
• Main Authors: Forbes, Gillian, Chen, Zhi-hui, Kin, Koryu, Lawal, Hajara M., Schilde, Christina, Yamada, Yoko, Schaap, Pauline
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.11.2019; BioMed Central; BMC
• Subjects: Amoebozoa; Amoebozoa - classification; Amoebozoa - genetics; Amoebozoa - growth & development; Amoebozoa - metabolism; Biological evolution; Cell differentiation; Comparative genomics; Comparative transcriptomics; Complexity; Conservation; Developmental stages; Dictyostelia; Dictyostelium - genetics; Differentiation (biology); DNA binding proteins; Domains; Evolution; Evolution (Biology); Evolution of phenotype; Evolution of transcriptional regulation; Evolution, Molecular; Experiments; Family relations; Fruit bodies; Functional analysis; Gene amplification; Gene expression; Gene Expression Regulation, Developmental; Gene regulation; Genes; Genetic aspects; Genetic regulation; Genomes; Genomics; Innovations; Phenotype; Phylogenetics; Phylogeny; Protein Domains; Proteins; Ribosomal DNA; Specialization; Spores; Taxa; Transcription (Genetics); Transcription factors; Transcription Factors - chemistry; Transcription Factors - genetics; Transcription Factors - metabolism; Transcriptome; Comparative genomics; Comparative transcriptomics; Amoebozoa; Dictyostelia; Evolution of phenotype; Evolution of transcriptional regulation

Dictyostelid social amoebas self-organize into fruiting bodies, consisting of spores and up to four supporting cell types in the phenotypically most complex taxon group 4. High quality genomes and stage- and cell-type specific transcriptomes are available for representative species of each of the fo...