CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells - Wei, Yongkun; Chen, Ya-Huey; Li, Long-Yuan; Lang, Jingyu; Yeh, Su-Peng; Shi, Bin; Yang, Cheng-Chieh; Yang, Jer-Yen; Lin, Chun-Yi; Lai, Chien-Chen; Hung, Mien-Chie (Nature cell biology, 2011)
Keywords: 2-Aminopurine - analogs & derivatives; 2-Aminopurine - pharmacology; 631/136/1660; 631/80/458/1648; 631/80/458/1733; 631/80/86; Antibodies; Biology; Biomedical and Life Sciences; Cancer; Cancer Research; Carrier Proteins - genetics; Carrier Proteins - metabolism; Catalysis; CDC2 Protein Kinase - antagonists & inhibitors; CDC2 Protein Kinase - genetics; CDC2 Protein Kinase - metabolism; Cell Biology; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cyclin-dependent kinases; Developmental Biology; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Enhancer of Zeste Homolog 2 Protein; Gene expression; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase - metabolism; Histones - metabolism; Humans; Immunoblotting; Invasiveness; Kinases; letter; Life Sciences; Lysine - metabolism; Mesenchymal Stem Cells - cytology; Mesenchymal Stem Cells - metabolism; Methylation; Neoplasm Proteins; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Oncology; Osteoblasts - cytology; Osteoblasts - metabolism; Phosphorylation; Physiological aspects; Polycomb Repressive Complex 2; Protein Binding; Protein kinases; Proteins; Repressor Proteins - genetics; Repressor Proteins - metabolism; RNA Interference; Stem Cells; Threonine - metabolism; Transcription Factors - genetics; Transcription Factors - metabolism; United States; Taiwan; United States--US; China