Type 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case-control study

• Published in: Paediatric and perinatal epidemiology Vol. 21; no. 6; pp. 507 - 517
• Main Authors: Eising, Stefanie, Svensson, Jannet, Skogstrand, Kristin, Nilsson, Anita, Lynch, Kristian, Andersen, Paal Skytt, Lernmark, Åke, Hougaard, David M., Pociot, Flemming, Nørgaard-Pedersen, Bent, Nerup, Jørn
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.11.2007
• Subjects: biomarkers; Biomarkers - blood; Blood Stains; Case-Control Studies; Clinical Medicine; cord blood; Denmark - epidemiology; Diabetes Mellitus, Type 1 - diagnosis; Diabetes Mellitus, Type 1 - etiology; Diabetes Mellitus, Type 1 - genetics; dried blood spots; Endocrinology and Diabetes; Endokrinologi och diabetes; Feasibility Studies; Female; Gene Amplification; Genetic Markers; Genotype; genotyping of candidate genes; Humans; Infant, Newborn; Klinisk medicin; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Predictive Value of Tests; Registries; Type 1 diabetes; Denmark

Summary Development of type 1 diabetes mellitus (T1D) may be triggered pre‐ or perinatally by multiple factors. Identifying new predisposing T1D markers or combinations of markers in a large, well‐characterised case–control collection may be important for future T1D prevention. The present work desc...