PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort - Mitchell, Kellie A.; Moore, Justin Xavier; Rosenson, Robert S.; Irvin, Ryan; Guirgis, Faheem W.; Shapiro, Nathan; Safford, Monika; Wang, Henry E. (PloS one, 2019)
Keywords: Adults; Aged; Analysis; Atherosclerosis; Biological markers; Biology and Life Sciences; Biomarkers; Biomarkers - blood; Black or African American - statistics & numerical data; Cholesterol; Cholesterol, LDL - blood; Cholesterol, LDL - metabolism; Chronic infection; Cohort Studies; Data processing; Emergency medical care; Epidemiology; Family medical history; Female; Health aspects; Health risks; Hospitalization; Hospitalization - statistics & numerical data; Humans; Independent Living - statistics & numerical data; Infection; Infections; Inflammation; Inflammatory response; Kexin; Lipids; Lipoproteins; Loss of Function Mutation; Low density lipoprotein; Low density lipoproteins; Male; Medicine; Medicine and Health Sciences; Metabolism; Middle Aged; Mortality; Movie propaganda; Proprotein Convertase 9 - genetics; Proprotein Convertase 9 - metabolism; Proprotein convertases; Proteins; Racial differences; Regression analysis; Risk; Risk factors; Sepsis; Sepsis - blood; Sepsis - epidemiology; Sepsis - genetics; Sepsis - therapy; Stroke; Subtilisin; United States - epidemiology; United States; Alabama; New York; United States--US