A Chinese version of the Language Screening Test (CLAST) for early-stage stroke patients

• Published in: PloS one Vol. 13; no. 5; p. e0196646
• Main Authors: Yang, Hongyan, Tian, Shenghua, Flamand-Roze, Constance, Gao, Ling, Zhang, Wei, Li, Yan, Wang, Jiajia, Sun, Zhou, Su, Ying, Zhao, Libin, Liang, Zhihou
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 04.05.2018; Public Library of Science (PLoS)
• Subjects: Aphasia; Aphasia - diagnosis; Asian Continental Ancestry Group; Biology and Life Sciences; Correlation; Correlation coefficient; Correlation coefficients; Education; Equivalence; Female; France; Humans; Language; Language Tests; Medical screening; Medical tests; Medicine and Health Sciences; Methods; Middle Aged; Neurology; Neuropsychological Tests; Patients; People and Places; Redundancy; Reliability analysis; Reproducibility of Results; Screening; Semantics; Sensitivity and Specificity; Social Sciences; Speeches; Stroke; Stroke - diagnosis; United States > US; Mississippi; China
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0196646

There is a severe lack of aphasia screening tools for bedside use in Chinese. A number of aphasia assessment tools have recently been developed abroad, but some of these scales were not suitable for patients with acute stroke. The Language Screening Test (which includes two parallel versions [a/b]) in French has been proven to be an effective and time-saving aphasia screening scale for early-stage stroke patients. Therefore, we worked out a Chinese version of the LAST taking into consideration Chinese language and culture. Two preliminary parallel versions (a/b) were tested on 154 patients with stroke at acute phase and 107 patients with stroke at non-acute phase, with the Western Aphasia Battery serving as a gold standard. The equivalence between the two parallel versions and the reliability/validity of each version were assessed. The median time to complete one preliminary Chinese version (each had some item redundancy) was 98 seconds. Two final parallel versions were established after adjustment/elimination of the redundant items and were found to be equivalent (intra-class correlation coefficient: 0.991). Internal consistency is(Cronbach α for each version [a/b] was 0.956 and 0.965, respectively) good. Internal validity was fine: (a) no floor or ceiling effect/item redundancy; (b) construct validity revealed a 1-dimension structure, just like the French version. The higher educated subjects scored higher than their lower educated counterparts (p<0.01). The external validity: at the optimum cut-off point where the score of version a/b <14 in higher educated group(<13 in lower): the specificity of each version was 0.878/0.902(1/1 in lower) and sensitivity was 0.972/0.944(0.944/0.944 in lower). Inter-rater equivalence (intra-class correlation coefficient) was 1. The Chinese version of the Language Screening Test was proved to be an efficient and time-saving bedside aphasia screening tool for stroke patients at acute phase and can be used by an average medical physician.