Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment - Chai, Yuek Ling; Chong, Joyce R.; Raquib, Ainiah R.; Xu, Xin; Hilal, Saima; Venketasubramanian, Narayanaswamy; Tan, Boon Yeow; Kumar, Alan P.; Sethi, Gautam; Chen, Christopher P.; Lai, Mitchell K. P. (Scientific reports, 2021)
Keywords: 692/53; 692/617/375; Aged; Alzheimer Disease - diagnosis; Alzheimer Disease - metabolism; Alzheimer's disease; Atrophy; Atrophy - pathology; Biomarkers - blood; Brain - pathology; Case-Control Studies; Cerebrovascular diseases; Cerebrovascular Disorders - pathology; Cognition; Cognitive ability; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - metabolism; Cohort Studies; Cross-Sectional Studies; Cytokines; Dementia; Dementia disorders; Dementia, Vascular - diagnosis; Dementia, Vascular - metabolism; Dementia, Vascular - pathology; Disease; Female; Humanities and Social Sciences; Humans; Immunoassays; Inflammation; Interleukin 6; Interleukin 8; Interleukin-6 - analysis; Interleukin-6 - blood; Interleukin-8 - analysis; Interleukin-8 - blood; Magnetic Resonance Imaging - methods; Male; Medical imaging; Middle Aged; multidisciplinary; Neurodegeneration; Neurodegenerative diseases; Neuroimaging; Neuroimaging - methods; Osteopontin; Osteopontin - blood; Osteopontin - genetics; Osteopontin - metabolism; Risk factors; Science; Science (multidisciplinary); Singapore; Substantia alba; Tumor necrosis factor; Tumor Necrosis Factor-alpha - analysis; Tumor Necrosis Factor-alpha - blood; Tumor necrosis factor-TNF; Vascular dementia; Vascular diseases; Vascular Diseases - pathology; Singapore