Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study

• Published in: European journal of clinical nutrition Vol. 67; no. 12; pp. 1277 - 1283
• Main Authors: Reinders, I, van Ballegooijen, A J, Visser, M, Elshorbagy, A K, Refsum, H, Henry, R M A, Dekker, J M, Nijpels, G, Stehouwer, C D A, Brouwer, I A
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2013; Nature Publishing Group
• Subjects: 631/45/287/1183; 692/700/1421/1860/1445; Aged; alpha-Linolenic Acid - blood; Biological and medical sciences; Cardiovascular diseases; Cardiovascular system; Clinical Nutrition; Confidence intervals; Cross-Sectional Studies; Docosahexaenoic acid; Docosahexaenoic Acids - blood; Echocardiography; Eicosapentaenoic acid; Eicosapentaenoic Acid - blood; Epidemiology; Fatty acids; Fatty Acids, Omega-3 - blood; Fatty Acids, Omega-6 - blood; Feeding. Feeding behavior; Female; Fish oils; Fundamental and applied biological sciences. Psychology; Gas liquid chromatography; Health aspects; Heart Atria - diagnostic imaging; Heart function; Heart Rate; Heart Ventricles - diagnostic imaging; Humans; Internal Medicine; Investigative techniques, diagnostic techniques (general aspects); Linoleic acid; Linoleic Acid - blood; Linolenic acid; Liquid chromatography; Male; Medical sciences; Medicine; Medicine & Public Health; Metabolic Diseases; Middle Aged; Older people; original-article; Physiological aspects; Polyunsaturated fatty acids; Population studies; Public Health; Quartiles; Regression analysis; Regression coefficients; Risk factors; Statistical analysis; Stroke Volume; Ultrasonic imaging; Ultrasonic investigative techniques; Unsaturated fatty acids; Ventricle; Ventricular Function, Left; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Netherlands; epidemiology; systolic function; elderly; polyunsaturated fatty acids; echocardiography; Sonography; Human; Echocardiography; Polyunsaturated fatty acid; Lipids; Metabolic diseases; Epidemiology; n-6 fatty acid; Association; Unsaturated fatty acid; Serum; Elderly

BACKGROUND/OBJECTIVES: Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n -3 and n -6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-section...