Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study
BACKGROUND/OBJECTIVES: Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n -3 and n -6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-section...
Saved in:
| Published in | European journal of clinical nutrition Vol. 67; no. 12; pp. 1277 - 1283 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
01.12.2013
Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | BACKGROUND/OBJECTIVES:
Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of
n
-3 and
n
-6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up.
SUBJECTS/METHODS:
We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.6±6.8 years at baseline. We performed linear regression analyses using
n
-3 and
n
-6 PUFAs quartiles—assayed by gas liquid chromatography—with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate.
RESULTS:
In multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0;
P
for trend <0.001) and 3.4 b.p.m. (1.2, 5.6;
P
for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of −4.0% compared with the highest quartile.
CONCLUSIONS:
This study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function. |
|---|---|
| AbstractList | Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n-3 and n-6 PUFAs were associated with less favorable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up. We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.6±6.8 years at baseline. We performed linear regression analyses using n-3 and n-6 PUFAs quartiles-assayed by gas liquid chromatography-with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate. In multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0; P for trend <0.001) and 3.4 b.p.m. (1.2, 5.6; P for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of -4.0% compared with the highest quartile. This study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function.[PUBLICATION ABSTRACT] BACKGROUND/OBJECTIVES:Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n-3 and n-6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up.SUBJECTS/METHODS:We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.6±6.8 years at baseline. We performed linear regression analyses using n-3 and n-6 PUFAs quartiles—assayed by gas liquid chromatography—with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate.RESULTS:In multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0; P for trend <0.001) and 3.4 b.p.m. (1.2, 5.6; P for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of −4.0% compared with the highest quartile.CONCLUSIONS:This study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function. SUBJECTS/METHODS: We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.616.8 years at baseline. We performed linear regression analyses using n-3 and n-6 PUFAs quartiles--assayed by gas liquid chromatography--with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate. European Journal of Clinical Nutrition (2013) 67, 1277-1283; doi: 10.1038/ejcn.2013.167; published online 2 October 2013 BACKGROUND/OBJECTIVES: Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n -3 and n -6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up. SUBJECTS/METHODS: We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.6±6.8 years at baseline. We performed linear regression analyses using n -3 and n -6 PUFAs quartiles—assayed by gas liquid chromatography—with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate. RESULTS: In multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0; P for trend <0.001) and 3.4 b.p.m. (1.2, 5.6; P for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of −4.0% compared with the highest quartile. CONCLUSIONS: This study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function. BACKGROUND/OBJECTIVES: Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n-3 and n-6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up. SUBJECTS/METHODS: We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.616.8 years at baseline. We performed linear regression analyses using n-3 and n-6 PUFAs quartiles--assayed by gas liquid chromatography--with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate. RESULTS: In multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0; P for trend <0.001) and 3.4 b.p.m. (1.2, 5.6;P for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of -4.0% compared with the highest quartile. CONCLUSIONS: This study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function. European Journal of Clinical Nutrition (2013) 67, 1277-1283; doi: 10.1038/ejcn.2013.167; published online 2 October 2013 Keywords: polyunsaturated fatty acids; elderly; epidemiology; echocardiography; systolic function Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n-3 and n-6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up. We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.6±6.8 years at baseline. We performed linear regression analyses using n-3 and n-6 PUFAs quartiles-assayed by gas liquid chromatography-with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate. In multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0; P for trend <0.001) and 3.4 b.p.m. (1.2, 5.6; P for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of -4.0% compared with the highest quartile. This study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function. BACKGROUND/OBJECTIVESLower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n-3 and n-6 PUFAs were associated with less favourable echocardiographic measures and higher heart rate in older Caucasians, cross-sectionally and after 7 years of follow-up.SUBJECTS/METHODSWe used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data for 336 participants. Mean age was 68.6±6.8 years at baseline. We performed linear regression analyses using n-3 and n-6 PUFAs quartiles-assayed by gas liquid chromatography-with left ventricular ejection fraction (LVEF), left ventricular mass index, left atrial volume index and heart rate.RESULTSIn multivariable analyses (regression coefficient (95% confidence interval)), the lowest eicosapentaenoic acid and docosahexaenoic acid quartiles compared with the highest quartiles were cross-sectionally associated with lower LVEF. Lower eicosapentaenoic acid and docosahexaenoic acid concentrations were associated with higher heart rate: 3.7 b.p.m. (1.5, 6.0; P for trend <0.001) and 3.4 b.p.m. (1.2, 5.6; P for trend 0.001), respectively. Multivariate longitudinal analyses showed a significant trend across quartiles for alpha-linolenic acid in relation to LVEF. The lowest linoleic acid quartile was significantly associated with a decreased LVEF of -4.0% compared with the highest quartile.CONCLUSIONSThis study found no strong evidence of longitudinal associations of eicosapentaenoic acid and docosahexaenoic acid with echocardiographic measures, however, lower concentrations of alpha-linolenic acid and linoleic acid were associated with decreased LVEF. These results provide evidence for a potential protective role of alpha-linolenic acid and linoleic acid in relation to systolic function. |
| Audience | Professional Academic |
| Author | Nijpels, G Brouwer, I A Refsum, H Henry, R M A van Ballegooijen, A J Reinders, I Elshorbagy, A K Visser, M Dekker, J M Stehouwer, C D A |
| Author_xml | – sequence: 1 givenname: I surname: Reinders fullname: Reinders, I email: ilse.reinders@vu.nl organization: Department of Health Sciences, EMGO+ Institute, VU University – sequence: 2 givenname: A J surname: van Ballegooijen fullname: van Ballegooijen, A J organization: Department of Health Sciences, EMGO+ Institute, VU University – sequence: 3 givenname: M surname: Visser fullname: Visser, M organization: Department of Health Sciences, EMGO+ Institute, VU University, Department of Epidemiology and Biostatistics, EMGO+ Institute, VU University Medical Center – sequence: 4 givenname: A K surname: Elshorbagy fullname: Elshorbagy, A K organization: Department of Pharmacology, University of Oxford, Oxford, Department of Physiology, Faculty of Medicine, University of Alexandria – sequence: 5 givenname: H surname: Refsum fullname: Refsum, H organization: Department of Pharmacology, University of Oxford, Oxford, Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo – sequence: 6 givenname: R M A surname: Henry fullname: Henry, R M A organization: Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre – sequence: 7 givenname: J M surname: Dekker fullname: Dekker, J M organization: Department of Epidemiology and Biostatistics, EMGO+ Institute, VU University Medical Center – sequence: 8 givenname: G surname: Nijpels fullname: Nijpels, G organization: Department of General Practice, EMGO+ Institute, VU University Medical Center – sequence: 9 givenname: C D A surname: Stehouwer fullname: Stehouwer, C D A organization: Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre – sequence: 10 givenname: I A surname: Brouwer fullname: Brouwer, I A organization: Department of Health Sciences, EMGO+ Institute, VU University |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27960838$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/24084512$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9ks-LEzEUx4OsuLvVo1cJiOJlapLJTGa8lUVdYcGDeh7S5KWTMpPU_EB69D831WpXKZLDg7zP-_29RhfOO0DoKSVLSuruNWyVWzJC6yVtxQN0Rbloq6bl5AJdkb7hVU2IuETXMW4JKU7BHqFLxknHG8qu0PdVjF5Zmax3EXuDI4Q8Y1fVWDpdbIt3ftpnF2XKQSbQ2MiU9lgqqyP-ZtOIQY1eyaCt3wS5G63CM8iYA0QsZ-822E8aApY6Tym-wWkEfOt9cPhTynr_GD00corw5GgX6Mu7t59vbqu7j-8_3KzuKtX0dao01azuiRGNZkq1a8rrtWgIp0ZowaUBQ2vC5Bq6hq8b02pQFKhRfSM4GM3rBXr1K-8u-K8ZYhpmGxVMk3TgcxwobxsqesZEQZ__g259Dq50N7CWs65mgrP_USUXbynrSXeiNnKCwTrjU5DqUHpY1Q1vC1buuEDVGWoDDoKcysGNLd9_8cszfHkaZqvOBry8FzCCnNIY_ZR_3v1sJyr4GAOYYRfsLMN-oGQ4KG44KG44KG4oiiv8s-MW8noG_Yf-LbECvDgCMio5mSCdsvHEib4ta-pOI8XichsI99Z5tvIPyYns5g |
| CitedBy_id | crossref_primary_10_1016_j_numecd_2020_09_001 crossref_primary_10_1017_S0029665115004255 crossref_primary_10_1017_S0007114516000933 crossref_primary_10_1016_j_plefa_2021_102378 crossref_primary_10_1024_0300_9831_a000612 |
| Cites_doi | 10.1016/j.jacc.2010.11.017 10.1016/j.ehj.2004.06.038 10.2337/diacare.27.2.522 10.3945/ajcn.2010.29182 10.2337/diacare.25.10.1784 10.2337/diacare.18.9.1270 10.1016/j.ahj.2011.02.011 10.1093/eurheartj/ehm605 10.1093/ajcn/85.3.755 10.1016/j.jacc.2011.06.063 10.1161/01.CIR.0000065222.34933.FC 10.1016/j.amjmed.2005.04.013 10.1161/CIRCULATIONAHA.105.556886 10.1186/1472-6963-12-103 10.1016/j.biochi.2009.01.008 10.1079/PHN2002391 10.1093/eurjhf/hfq172 10.1016/j.clnu.2012.05.010 10.3945/ajcn.2009.28500 10.1371/journal.pmed.1001255 10.1136/bmj.e8707 10.1016/j.jacc.2004.09.054 10.1161/CIR.0b013e318245fac5 10.1097/00004872-200208000-00010 10.1530/EC-12-0033 10.1016/j.amjcard.2005.08.025 |
| ContentType | Journal Article |
| Copyright | Macmillan Publishers Limited 2013 2015 INIST-CNRS COPYRIGHT 2013 Nature Publishing Group Copyright Nature Publishing Group Dec 2013 Macmillan Publishers Limited 2013. |
| Copyright_xml | – notice: Macmillan Publishers Limited 2013 – notice: 2015 INIST-CNRS – notice: COPYRIGHT 2013 Nature Publishing Group – notice: Copyright Nature Publishing Group Dec 2013 – notice: Macmillan Publishers Limited 2013. |
| DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7QP 7RV 7TK 7X2 7X7 7XB 88E 8AO 8C1 8FE 8FH 8FI 8FJ 8FK 8G5 ABUWG AFKRA AN0 ATCPS AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ GUQSH HCIFZ K9. KB0 LK8 M0K M0S M1P M2O M7P MBDVC NAPCQ PQEST PQQKQ PQUKI Q9U 7X8 |
| DOI | 10.1038/ejcn.2013.167 |
| DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Calcium & Calcified Tissue Abstracts Nursing & Allied Health Database Neurosciences Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni Edition) ProQuest Central (Alumni) ProQuest Central British Nursing Database Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Research Library Prep SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Biological Sciences Agriculture Science Database Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Research Library Biological Science Database Research Library (Corporate) Nursing & Allied Health Premium ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central Basic MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Agricultural Science Database Research Library Prep ProQuest Central Student ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College Research Library (Alumni Edition) ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Agricultural & Environmental Science Collection Biological Science Collection ProQuest Research Library ProQuest Medical Library (Alumni) ProQuest Public Health ProQuest Biological Science Collection ProQuest Central Basic ProQuest One Academic Eastern Edition Agricultural Science Collection British Nursing Index with Full Text ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | Agricultural Science Database Agricultural Science Database MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Databases url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Public Health Anatomy & Physiology Diet & Clinical Nutrition |
| EISSN | 1476-5640 |
| EndPage | 1283 |
| ExternalDocumentID | 3144642111 A354661210 10_1038_ejcn_2013_167 24084512 27960838 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | Netherlands |
| GeographicLocations_xml | – name: Netherlands |
| GroupedDBID | --- -ET -Q- .GJ 0R~ 29G 2WC 36B 39C 3V. 4.4 406 53G 5GY 5RE 6PF 70F 7RV 7X2 7X7 88E 8AO 8C1 8FE 8FH 8FI 8FJ 8G5 8R4 8R5 A8Z AACDK AAHBH AAIKC AAMNW AANZL AASML AATNV AAWBL AAWTL AAZLF ABAKF ABAWZ ABCQX ABDBF ABJNI ABLJU ABOCM ABUWG ABZZP ACAOD ACGFO ACGFS ACKTT ACMJI ACPRK ACRQY ACZOJ ADBBV ADFRT ADHDB ADHUB AEFQL AEJRE AEMSY AENEX AEVLU AEXYK AFBBN AFKRA AFRAH AFSHS AGAYW AGEZK AGHAI AGQEE AHMBA AHSBF AI. AIGIU AILAN AJRNO ALFFA ALIPV ALMA_UNASSIGNED_HOLDINGS AMYLF AN0 APEBS ATCPS AXYYD AZQEC B0M BAWUL BBNVY BENPR BHPHI BKEYQ BKKNO BKOMP BNQBC BPHCQ BVXVI CCPQU CS3 DIK DNIVK DPUIP DU5 DWQXO E.L E3Z EAD EAP EAS EBC EBD EBLON EBO EBS ECGQY EE. EHN EIHBH EIOEI EJD EMB EMK EMOBN EPL EPT ESTFP ESX EX3 F5P FDQFY FERAY FIGPU FIZPM FSGXE FYUFA GNUQQ GUQSH HCIFZ HMCUK HZ~ IAG IAO ICU IEA IHR IHT IHW INH INR IOF ITC IWAJR JSO JZLTJ KQ8 LGEZI LOTEE M0K M1P M2O M7P NADUK NAO NAPCQ NQJWS NXXTH O9- OK1 OVD P2P PQQKQ PROAC PSQYO Q2X Q~Q RNS RNT RNTTT RXW SNX SNYQT SOHCF SRMVM SV3 SWTZT TAE TAOOD TBHMF TDRGL TEORI TH9 TR2 TSG TUS UKHRP VH1 WH7 WOW XOL ZXP ~02 ~8M ~KM 8W4 AADWK AALRV AAPBV AAYJO ABDEU ABFLS ABGIJ ABPTK ACBMV ACBRV ACBYP ACDSR ACIGE ACTTH ACVWB ADMDM ADQMX ADYYL AEDAW AEFTE AGGBP AJDOV AMRJV BBAFP IQODW N95 NYICJ PQEST PQUKI W2D AAYZH CGR CUY CVF ECM EIF NPM AAYXX CITATION AAYFA AFNRJ AJCLW 7QP 7TK 7XB 8FK K9. LK8 MBDVC Q9U 7X8 |
| ID | FETCH-LOGICAL-c593t-d1d2390f75d2cc6b143b75041f7d74afef1302abe854b5f6dec1e1fc9574efd43 |
| IEDL.DBID | BENPR |
| ISSN | 0954-3007 |
| IngestDate | Sat Aug 17 03:41:54 EDT 2024 Thu Oct 10 20:50:30 EDT 2024 Thu Oct 10 20:50:10 EDT 2024 Fri Feb 23 00:04:04 EST 2024 Fri Feb 02 05:17:12 EST 2024 Fri Feb 02 04:25:57 EST 2024 Tue Aug 20 22:13:42 EDT 2024 Thu Sep 26 15:44:01 EDT 2024 Tue Oct 15 23:46:21 EDT 2024 Fri Nov 25 06:02:58 EST 2022 Fri Oct 11 20:44:44 EDT 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | epidemiology systolic function elderly polyunsaturated fatty acids echocardiography Sonography Human Echocardiography Polyunsaturated fatty acid Lipids Metabolic diseases Epidemiology n-6 fatty acid Association Unsaturated fatty acid Serum Elderly |
| Language | English |
| License | CC BY 4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c593t-d1d2390f75d2cc6b143b75041f7d74afef1302abe854b5f6dec1e1fc9574efd43 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.nature.com/articles/ejcn2013167.pdf |
| PMID | 24084512 |
| PQID | 1464612908 |
| PQPubID | 33883 |
| PageCount | 7 |
| ParticipantIDs | proquest_miscellaneous_1465179227 proquest_journals_2642832742 proquest_journals_1464612908 gale_infotracmisc_A354661210 gale_infotracgeneralonefile_A354661210 gale_infotracacademiconefile_A354661210 gale_healthsolutions_A354661210 crossref_primary_10_1038_ejcn_2013_167 pubmed_primary_24084512 pascalfrancis_primary_27960838 springer_journals_10_1038_ejcn_2013_167 |
| PublicationCentury | 2000 |
| PublicationDate | 2013-12-01 |
| PublicationDateYYYYMMDD | 2013-12-01 |
| PublicationDate_xml | – month: 12 year: 2013 text: 2013-12-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: Basingstoke – name: England |
| PublicationTitle | European journal of clinical nutrition |
| PublicationTitleAbbrev | Eur J Clin Nutr |
| PublicationTitleAlternate | Eur J Clin Nutr |
| PublicationYear | 2013 |
| Publisher | Nature Publishing Group UK Nature Publishing Group |
| Publisher_xml | – name: Nature Publishing Group UK – name: Nature Publishing Group |
| References | Robertson, McElduff, Pearson, Henry, Inder, Attia (CR4) 2012; 12 Pritchett, Mahoney, Jacobsen, Rodeheffer, Karon, Redfield (CR19) 2005; 45 de Simone, Gottdiener, Chinali, Maurer (CR18) 2008; 29 van Ballegooijen, Visser, Snijder, Dekker, Nijpels, Stehouwer (CR20) 2012; 1 Mozaffarian, Gottdiener, Siscovick (CR23) 2006; 97 Mozaffarian, Wu (CR8) 2011; 58 van Dam, Snijder, Dekker, Stehouwer, Bouter, Heine (CR22) 2007; 85 Khaw, Friesen, Riboli, Luben, Wareham (CR11) 2012; 9 Spijkerman, Adriaanse, Dekker, Nijpels, Stehouwer, Bouter (CR15) 2002; 25 Mooy, Grootenhuis, de Vries, Valkenburg, Bouter, Kostense (CR14) 1995; 18 Ramsden, Zamora, Leelarthaepin, Majchrzak-Hong, Faurot, Suchindran (CR26) 2013; 346 Patel, Sharp, Jansen, Luben, Khaw, Wareham (CR13) 2010; 92 Bleumink, Knetsch, Sturkenboom, Straus, Hofman, Deckers (CR2) 2004; 25 Geleijnse, Giltay, Grobbee, Donders, Kok (CR5) 2002; 20 Ghio, Scelsi, Latini, Masson, Eleuteri, Palvarini (CR6) 2010; 12 Anderson, Nettleton, Hundley, Tsai, Steffen, Lemaitre (CR10) 2011; 2011 Goldberg, Spencer, Farmer, Meyer, Pezzella (CR3) 2005; 118 Arab, Akbar (CR28) 2002; 5 Henry, Kamp, Kostense, Spijkerman, Dekker, van Eijck (CR17) 2004; 27 Djoussé, Akinkuolie, Wu, Ding, Gaziano (CR12) 2012; 31 Roger, Go, Lloyd-Jones, Benjamin, Berry, Borden (CR1) 2012; 125 Henry, Kostense, Spijkerman, Dekker, Nijpels, Heine (CR16) 2003; 107 Choo, Ueshima, Curb, Shin, Evans, El-Saed (CR27) 2010; 91 Mozaffarian, Geelen, Brouwer, Geleijnse, Zock, Katan (CR9) 2005; 112 CR21 Moertl, Hammer, Steiner, Hutuleac, Vonbank, Berger (CR24) 2011; 161 Calder (CR25) 2009; 91 Nodari, Triggiani, Campia, Manerba, Milesi, Cesana (CR7) 2011; 57 AM Spijkerman (BFejcn2013167_CR15) 2002; 25 D Moertl (BFejcn2013167_CR24) 2011; 161 VL Roger (BFejcn2013167_CR1) 2012; 125 RJ Goldberg (BFejcn2013167_CR3) 2005; 118 KT Khaw (BFejcn2013167_CR11) 2012; 9 L Arab (BFejcn2013167_CR28) 2002; 5 D Mozaffarian (BFejcn2013167_CR9) 2005; 112 JS Anderson (BFejcn2013167_CR10) 2011; 2011 PS Patel (BFejcn2013167_CR13) 2010; 92 AJ van Ballegooijen (BFejcn2013167_CR20) 2012; 1 L Djoussé (BFejcn2013167_CR12) 2012; 31 GS Bleumink (BFejcn2013167_CR2) 2004; 25 CE Ramsden (BFejcn2013167_CR26) 2013; 346 G de Simone (BFejcn2013167_CR18) 2008; 29 S Ghio (BFejcn2013167_CR6) 2010; 12 PC Calder (BFejcn2013167_CR25) 2009; 91 RM Henry (BFejcn2013167_CR16) 2003; 107 BFejcn2013167_CR21 AM Pritchett (BFejcn2013167_CR19) 2005; 45 S Nodari (BFejcn2013167_CR7) 2011; 57 J Robertson (BFejcn2013167_CR4) 2012; 12 D Mozaffarian (BFejcn2013167_CR8) 2011; 58 J Choo (BFejcn2013167_CR27) 2010; 91 JM Mooy (BFejcn2013167_CR14) 1995; 18 JM Geleijnse (BFejcn2013167_CR5) 2002; 20 D Mozaffarian (BFejcn2013167_CR23) 2006; 97 RM Henry (BFejcn2013167_CR17) 2004; 27 RM van Dam (BFejcn2013167_CR22) 2007; 85 |
| References_xml | – volume: 57 start-page: 870 year: 2011 end-page: 879 ident: CR7 article-title: Effects of n-3 polyunsaturated fatty acids on left ventricular function and functional capacity in patients with dilated cardiomyopathy publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2010.11.017 contributor: fullname: Cesana – volume: 25 start-page: 1614 year: 2004 end-page: 1619 ident: CR2 article-title: Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study publication-title: Eur Heart J doi: 10.1016/j.ehj.2004.06.038 contributor: fullname: Deckers – volume: 27 start-page: 522 year: 2004 end-page: 529 ident: CR17 article-title: Left ventricular mass increases with deteriorating glucose tolerance, especially in women: independence of increased arterial stiffness or decreased flow-mediated dilation: the Hoorn study publication-title: Diabetes Care doi: 10.2337/diacare.27.2.522 contributor: fullname: van Eijck – volume: 92 start-page: 1214 year: 2010 end-page: 1222 ident: CR13 article-title: Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort publication-title: Am J Clin Nutr doi: 10.3945/ajcn.2010.29182 contributor: fullname: Wareham – volume: 25 start-page: 1784 year: 2002 end-page: 1789 ident: CR15 article-title: Diabetic patients detected by population-based stepwise screening already have a diabetic cardiovascular risk profile publication-title: Diabetes Care doi: 10.2337/diacare.25.10.1784 contributor: fullname: Bouter – volume: 18 start-page: 1270 year: 1995 end-page: 1273 ident: CR14 article-title: Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn Study publication-title: Diabetes Care doi: 10.2337/diacare.18.9.1270 contributor: fullname: Kostense – volume: 161 start-page: e911 year: 2011 end-page: e919 ident: CR24 article-title: Dose-dependent effects of omega-3-polyunsaturated fatty acids on systolic left ventricular function, endothelial function, and markers of inflammation in chronic heart failure of nonischemic origin: a double-blind, placebo-controlled, 3-arm study publication-title: Am Heart J doi: 10.1016/j.ahj.2011.02.011 contributor: fullname: Berger – volume: 29 start-page: 741 year: 2008 end-page: 747 ident: CR18 article-title: Left ventricular mass predicts heart failure not related to previous myocardial infarction: the Cardiovascular Health Study publication-title: Eur Heart J doi: 10.1093/eurheartj/ehm605 contributor: fullname: Maurer – volume: 2011 start-page: 315134 year: 2011 ident: CR10 article-title: Associations of plasma phospholipid omega-6 and omega-3 polyunsaturated fatty acid levels and MRI measures of cardiovascular structure and function: the multiethnic study of atherosclerosis publication-title: J Nutr Metab contributor: fullname: Lemaitre – volume: 85 start-page: 755 year: 2007 end-page: 761 ident: CR22 article-title: Potentially modifiable determinants of vitamin D status in an older population in The Netherlands: the Hoorn Study publication-title: Am J Clin Nutr doi: 10.1093/ajcn/85.3.755 contributor: fullname: Heine – volume: 58 start-page: 2047 year: 2011 end-page: 2067 ident: CR8 article-title: Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2011.06.063 contributor: fullname: Wu – volume: 107 start-page: 2089 year: 2003 end-page: 2095 ident: CR16 article-title: Arterial stiffness increases with deteriorating glucose tolerance status: the Hoorn Study publication-title: Circulation doi: 10.1161/01.CIR.0000065222.34933.FC contributor: fullname: Heine – volume: 118 start-page: 728 year: 2005 end-page: 734 ident: CR3 article-title: Incidence and hospital death rates associated with heart failure: a community-wide perspective publication-title: Am J Med doi: 10.1016/j.amjmed.2005.04.013 contributor: fullname: Pezzella – volume: 112 start-page: 1945 year: 2005 end-page: 1952 ident: CR9 article-title: Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.105.556886 contributor: fullname: Katan – volume: 12 start-page: 103 year: 2012 ident: CR4 article-title: The health services burden of heart failure: an analysis using linked population health data-sets publication-title: BMC Health Serv Res doi: 10.1186/1472-6963-12-103 contributor: fullname: Attia – ident: CR21 – volume: 91 start-page: 791 year: 2009 end-page: 795 ident: CR25 article-title: Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale publication-title: Biochimie doi: 10.1016/j.biochi.2009.01.008 contributor: fullname: Calder – volume: 5 start-page: 865 year: 2002 end-page: 871 ident: CR28 article-title: Biomarkers and the measurement of fatty acids publication-title: Public Health Nutr doi: 10.1079/PHN2002391 contributor: fullname: Akbar – volume: 12 start-page: 1345 year: 2010 end-page: 1353 ident: CR6 article-title: Effects of n–3 polyunsaturated fatty acids and of rosuvastatin on left ventricular function in chronic heart failure: a substudy of GISSI-HF trial publication-title: Eur J Heart Failure doi: 10.1093/eurjhf/hfq172 contributor: fullname: Palvarini – volume: 31 start-page: 846 year: 2012 end-page: 853 ident: CR12 article-title: Fish consumption, omega-3 fatty acids and risk of heart failure: a meta-analysis publication-title: Clin Nutr doi: 10.1016/j.clnu.2012.05.010 contributor: fullname: Gaziano – volume: 91 start-page: 1195 year: 2010 end-page: 1203 ident: CR27 article-title: Serum n-6 fatty acids and lipoprotein subclasses in middle-aged men: the population-based cross-sectional ERA-JUMP study publication-title: Am J Clin Nutr doi: 10.3945/ajcn.2009.28500 contributor: fullname: El-Saed – volume: 9 start-page: e1001255 year: 2012 ident: CR11 article-title: Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study publication-title: PLoS Med doi: 10.1371/journal.pmed.1001255 contributor: fullname: Wareham – volume: 346 start-page: e8707 year: 2013 ident: CR26 article-title: Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis publication-title: BMJ doi: 10.1136/bmj.e8707 contributor: fullname: Suchindran – volume: 45 start-page: 87 year: 2005 end-page: 92 ident: CR19 article-title: Diastolic dysfunction and left atrial volume: a population-based study publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2004.09.054 contributor: fullname: Redfield – volume: 125 start-page: e2 year: 2012 end-page: e220 ident: CR1 article-title: Heart disease and stroke statistics -2012 update: a report from the American Heart Association publication-title: Circulation doi: 10.1161/CIR.0b013e318245fac5 contributor: fullname: Borden – volume: 20 start-page: 1493 year: 2002 end-page: 1499 ident: CR5 article-title: Blood pressure response to fish oil supplementation: metaregression analysis of randomized trials publication-title: J Hypertens doi: 10.1097/00004872-200208000-00010 contributor: fullname: Kok – volume: 1 start-page: 48 year: 2012 end-page: 57 ident: CR20 article-title: Serum 25-hydroxyvitamin D and parathyroid hormone in relation to plasma B-type natriuretic peptide: the Hoorn Study publication-title: Endocr Connect doi: 10.1530/EC-12-0033 contributor: fullname: Stehouwer – volume: 97 start-page: 216 year: 2006 end-page: 222 ident: CR23 article-title: Intake of tuna or other broiled or baked fish versus fried fish and cardiac structure, function, and hemodynamics publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2005.08.025 contributor: fullname: Siscovick – volume: 18 start-page: 1270 year: 1995 ident: BFejcn2013167_CR14 publication-title: Diabetes Care doi: 10.2337/diacare.18.9.1270 contributor: fullname: JM Mooy – volume: 5 start-page: 865 year: 2002 ident: BFejcn2013167_CR28 publication-title: Public Health Nutr doi: 10.1079/PHN2002391 contributor: fullname: L Arab – volume: 2011 start-page: 315134 year: 2011 ident: BFejcn2013167_CR10 publication-title: J Nutr Metab contributor: fullname: JS Anderson – volume: 125 start-page: e2 year: 2012 ident: BFejcn2013167_CR1 publication-title: Circulation doi: 10.1161/CIR.0b013e318245fac5 contributor: fullname: VL Roger – volume: 161 start-page: e911 year: 2011 ident: BFejcn2013167_CR24 publication-title: Am Heart J doi: 10.1016/j.ahj.2011.02.011 contributor: fullname: D Moertl – volume: 31 start-page: 846 year: 2012 ident: BFejcn2013167_CR12 publication-title: Clin Nutr doi: 10.1016/j.clnu.2012.05.010 contributor: fullname: L Djoussé – volume: 107 start-page: 2089 year: 2003 ident: BFejcn2013167_CR16 publication-title: Circulation doi: 10.1161/01.CIR.0000065222.34933.FC contributor: fullname: RM Henry – volume: 112 start-page: 1945 year: 2005 ident: BFejcn2013167_CR9 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.105.556886 contributor: fullname: D Mozaffarian – volume: 45 start-page: 87 year: 2005 ident: BFejcn2013167_CR19 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2004.09.054 contributor: fullname: AM Pritchett – volume: 85 start-page: 755 year: 2007 ident: BFejcn2013167_CR22 publication-title: Am J Clin Nutr doi: 10.1093/ajcn/85.3.755 contributor: fullname: RM van Dam – volume: 12 start-page: 103 year: 2012 ident: BFejcn2013167_CR4 publication-title: BMC Health Serv Res doi: 10.1186/1472-6963-12-103 contributor: fullname: J Robertson – volume: 12 start-page: 1345 year: 2010 ident: BFejcn2013167_CR6 publication-title: Eur J Heart Failure doi: 10.1093/eurjhf/hfq172 contributor: fullname: S Ghio – volume: 29 start-page: 741 year: 2008 ident: BFejcn2013167_CR18 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehm605 contributor: fullname: G de Simone – ident: BFejcn2013167_CR21 – volume: 25 start-page: 1614 year: 2004 ident: BFejcn2013167_CR2 publication-title: Eur Heart J doi: 10.1016/j.ehj.2004.06.038 contributor: fullname: GS Bleumink – volume: 58 start-page: 2047 year: 2011 ident: BFejcn2013167_CR8 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2011.06.063 contributor: fullname: D Mozaffarian – volume: 1 start-page: 48 year: 2012 ident: BFejcn2013167_CR20 publication-title: Endocr Connect doi: 10.1530/EC-12-0033 contributor: fullname: AJ van Ballegooijen – volume: 20 start-page: 1493 year: 2002 ident: BFejcn2013167_CR5 publication-title: J Hypertens doi: 10.1097/00004872-200208000-00010 contributor: fullname: JM Geleijnse – volume: 91 start-page: 791 year: 2009 ident: BFejcn2013167_CR25 publication-title: Biochimie doi: 10.1016/j.biochi.2009.01.008 contributor: fullname: PC Calder – volume: 25 start-page: 1784 year: 2002 ident: BFejcn2013167_CR15 publication-title: Diabetes Care doi: 10.2337/diacare.25.10.1784 contributor: fullname: AM Spijkerman – volume: 346 start-page: e8707 year: 2013 ident: BFejcn2013167_CR26 publication-title: BMJ doi: 10.1136/bmj.e8707 contributor: fullname: CE Ramsden – volume: 9 start-page: e1001255 year: 2012 ident: BFejcn2013167_CR11 publication-title: PLoS Med doi: 10.1371/journal.pmed.1001255 contributor: fullname: KT Khaw – volume: 57 start-page: 870 year: 2011 ident: BFejcn2013167_CR7 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2010.11.017 contributor: fullname: S Nodari – volume: 92 start-page: 1214 year: 2010 ident: BFejcn2013167_CR13 publication-title: Am J Clin Nutr doi: 10.3945/ajcn.2010.29182 contributor: fullname: PS Patel – volume: 91 start-page: 1195 year: 2010 ident: BFejcn2013167_CR27 publication-title: Am J Clin Nutr doi: 10.3945/ajcn.2009.28500 contributor: fullname: J Choo – volume: 27 start-page: 522 year: 2004 ident: BFejcn2013167_CR17 publication-title: Diabetes Care doi: 10.2337/diacare.27.2.522 contributor: fullname: RM Henry – volume: 97 start-page: 216 year: 2006 ident: BFejcn2013167_CR23 publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2005.08.025 contributor: fullname: D Mozaffarian – volume: 118 start-page: 728 year: 2005 ident: BFejcn2013167_CR3 publication-title: Am J Med doi: 10.1016/j.amjmed.2005.04.013 contributor: fullname: RJ Goldberg |
| SSID | ssj0014772 |
| Score | 2.1563363 |
| Snippet | BACKGROUND/OBJECTIVES:
Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of... Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of n-3 and n-6 PUFAs were... BACKGROUND/OBJECTIVES: Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of... SUBJECTS/METHODS: We used data from the Hoorn Study, a population-based cohort. Cross-sectional data were available for 621 participants and longitudinal data... BACKGROUND/OBJECTIVES:Lower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of... BACKGROUND/OBJECTIVESLower circulating polyunsaturated fatty acids (PUFAs) may induce loss of heart function. We investigated whether lower concentrations of... |
| SourceID | proquest gale crossref pubmed pascalfrancis springer |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 1277 |
| SubjectTerms | 631/45/287/1183 692/700/1421/1860/1445 Aged alpha-Linolenic Acid - blood Biological and medical sciences Cardiovascular diseases Cardiovascular system Clinical Nutrition Confidence intervals Cross-Sectional Studies Docosahexaenoic acid Docosahexaenoic Acids - blood Echocardiography Eicosapentaenoic acid Eicosapentaenoic Acid - blood Epidemiology Fatty acids Fatty Acids, Omega-3 - blood Fatty Acids, Omega-6 - blood Feeding. Feeding behavior Female Fish oils Fundamental and applied biological sciences. Psychology Gas liquid chromatography Health aspects Heart Atria - diagnostic imaging Heart function Heart Rate Heart Ventricles - diagnostic imaging Humans Internal Medicine Investigative techniques, diagnostic techniques (general aspects) Linoleic acid Linoleic Acid - blood Linolenic acid Liquid chromatography Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle Aged Older people original-article Physiological aspects Polyunsaturated fatty acids Population studies Public Health Quartiles Regression analysis Regression coefficients Risk factors Statistical analysis Stroke Volume Ultrasonic imaging Ultrasonic investigative techniques Unsaturated fatty acids Ventricle Ventricular Function, Left Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| Title | Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study |
| URI | https://link.springer.com/article/10.1038/ejcn.2013.167 https://www.ncbi.nlm.nih.gov/pubmed/24084512 https://www.proquest.com/docview/1464612908 https://www.proquest.com/docview/2642832742 https://search.proquest.com/docview/1465179227 |
| Volume | 67 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9NAEF7R9oKEELQ8DCUsEgonU9u79tpcUCitIiQihKiUm7XeBwpq7BA7hxz558ysN0kjIi6JlJ1knZ2H5-VvCHlbKZZZ8LMhyDFZyBOZhDLTJtQQMislVMoqrOh-nWTjG_5lmk59wq31bZUbm-gMtW4U5sgvQKN5hkmT_OPid4hTo7C66kdoHJGTJOZYpj35dDX59n1bR-DCjW8CPwLz_5HwKJsRyy_ML4X4pzF7H7sh87u7krfNDxayhXOy_YCLQx7oP9VTd1O6fkQeem-Sjnr2Pyb3TH1KzkY1RNLzNR1S19_pEuenJPg8Mx185pFAb-lkA8R_Rv7c4VJLG0tBMFdzWoeMylrDe0YXze16VbeIAwruqaZWdt2aSjXTLcVkLjVgSJXrbnUg2DNF533-saVuohFtcCA4dYAf7QcKjicdN82yptjKuH5Cbq6vflyOQz-cIVRpwbpQxzphRWRFqhOlsgr8rgqh4mMrtODSGoslUVmZPOVVaoH_KjaxVUUquLGas6fkuG5q85xQkcsoUoWRViBUjigiBkaXIfa-LhKbBWS4YU656DE4Slc7Z3mJXCyRiyVwMSCvkXVl_wjpVnfLEUt55qDSAvLOUaD2dkuppH8IAS4EcbD2KId7lD97FPBDhOd7hKCeam95sCdH23-QCAgec5bD9zeCVXr70ZY7aT-4nGDUyLDKHpA322XcGVvmatOs3E8g_FqSwLE86-V1tzePcg6uHhzHRoDv7H3oaF_8_ypfkvtI2ff5nJPjbrkyr8Bb66oBORJTAa_5ZTzw6vkXaPw_bw |
| link.rule.ids | 315,786,790,12083,12250,21416,27955,27956,31752,31753,33299,33300,33777,33778,43343,43612,43838,74100,74369,74657 |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9NAEF5BOYCEELQ8AqUdJFROprZ37bW5oKhQBWhzaqXerPU-UFBjh9g55Mg_Z2btJI2IOFnKjr3Ozux4XvsNY-9LzVOHdjY6OTYNRKziQKXGBgZdZq2lTnhJGd3LcTq6Ft9vkps-4Nb0ZZUrnegVtak1xchPcUeLlIIm2efZ74C6RlF2tW-hcZ89EBxH6aT42brEIxLSN29CK4Ki_6HsMTZDnp3aX5rQTyP-MfIt5jffpF4zP56pBlfJde0tdtmf_-RO_Sfp_Cl70tuSMOyY_4zds9U-OxhW6EdPl3ACvrrTh8332eDLxLb4W48DegvjFQz_Aftzh0cN1A5QLBdTqAIOqjJ4TWFW3y4XVUMooGicGnCqbZeg9MQ0QKFcsKhGta9t9RDYEw3TLvrYgO9nBDW1AwcP99F8AjQ7YVTX8wqokHH5nF2ff706GwV9a4ZAJzlvAxOZmOehk4mJtU5LtLpKAoqPnDRSKGcdJURVabNElIlD7uvIRk7niRTWGcFfsL2qruwrBjJTYahzq5wkoByZhxxVLifkfZPHLh2wkxVzilmHwFH4zDnPCuJiQVwskIsDdkysK7oDpOudWwx5IlIPlDZgHzwF7d12rrTqjyDgixAK1hblyRblzw4DfBfh4RYhbk69NXy0JUfrfxBLdB0znuH9K8Eqeu3RFBtZ3zkck8_IKcc-YO_WwzQzFcxVtl74RxD4Whzjsrzs5HUztwgzgYYeLsdKgO_MvWtpX___LY_Zw9HV5UVx8W384w17RHd1FT-HbK-dL-xbtNva8shvzr_aUD8N |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Jj9MwFLZgkBDSCMEMS2GYMRIqp9AkduKEC6oYqrJVHBipt8jxgoqmSadJDz3yz3nPcdupqDhFqp049Vv8tnyPkDelYqkFOxucHJMGPJZxIFNtAg0us1JCJazEjO73STq-4l-mydTXPzW-rHKjE52i1rXCGPkAJJqnGDTJBtaXRfy4HH1Y3ATYQQozrb6dxl1yD07JENs4iOnW-Yq4cI2cwKLATEAoPN5myLKB-a0QCTVi7yLXbn53PnktfbyQDeyY7VpdHLJF_8mjuuNp9Ig89HYlHXaM8JjcMdUJOR1W4FPP17RPXaWnC6GfkN7lzLTwm8cEvaaTDST_Kflzi14NrS0FFl3NaRUwKisN15Qu6uv1qmoQERQMVU2tbNs1lWqmG4phXWpApSpX5-rgsGeKzrtIZENdbyNaY2tw6qA_mvcUTFA6rutlRbGocf2EXI0-_fw4DnybhkAlOWsDHemY5aEViY6VSkuwwEoEjY-s0IJLaywmR2VpsoSXiQVOUJGJrMoTwY3VnD0lR1VdmeeEikyGocqNtAJBc0QeMlC_DFH4dR7btEf6G-IUiw6No3BZdJYVSMUCqVgAFXvkAklXdB-TbqW4GLKEpw40rUfeuhkox-1SKuk_R4AXQUSsvZn9vZm_OjzwQxPP9iaCoKq94fM9Ptr-g1iAG5mxDO7fMFbhNUlT7Pj-4HCM_iPDfHuPvN4O48pYPFeZeuUegUBscQzb8qzj193aPMw4GH2wHRsGvrX2oa198f-3vCD3QS6Lb58nX1-SB3hTV_xzRo7a5cq8AhOuLc-dbP4FVAZDbg |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Associations+of+serum+n-3+and+n-6+polyunsaturated+fatty+acids+with+echocardiographic+measures+among+older+adults%3A+the+Hoorn+study&rft.jtitle=European+journal+of+clinical+nutrition&rft.au=Reinders%2C+I&rft.au=van+Ballegooijen%2C+A.J&rft.au=Visser%2C+M&rft.au=Elshorbagy%2C+A.K&rft.date=2013-12-01&rft.pub=Nature+Publishing+Group&rft.issn=0954-3007&rft.eissn=1476-5640&rft.volume=67&rft.issue=12&rft.spage=1277&rft_id=info:doi/10.1038%2Fejcn.2013.167&rft.externalDocID=A354661210 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0954-3007&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0954-3007&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0954-3007&client=summon |