Impact of Obstructive Sleep Apnea on the Atrial Electromechanical Activation Time
Background Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the association between OSA and atrial remodeling has not been fully elucidated. Methods and Results Atrial electromechanical activation time (...
Saved in:
| Published in | Circulation Journal Vol. 73; no. 2; pp. 249 - 255 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Japan
The Japanese Circulation Society
2009
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1346-9843 1347-4820 |
| DOI | 10.1253/circj.CJ-08-0813 |
Cover
| Abstract | Background Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the association between OSA and atrial remodeling has not been fully elucidated. Methods and Results Atrial electromechanical activation time (EMAT) was investigated using tissue Doppler imaging (TDI) in men with severe OSA (n=24) and control subjects (n=24). The EMAT was determined as the time interval from the initiation of P-wave deflection until the peak of local lateral left atrial (LA) TDI signal. The early diastolic velocity of the mitral annulus (Ea) and the EMAT were significantly lower and longer in OSA cases than in controls (Ea: 6.1±0.9 cm/s vs 7.3±1.5 cm/s, P=0.001; EMAT: 129.7±11.5 ms vs 118.5±12.3 ms, P=0.002). Among OSA cases, the apnea - hypopnea index (AHI) was significantly correlated with EMAT (r=0.660, P<0.001), Ea (r=-0.609, P=0.002), LA dimension (r=0.486, P=0.016), and early diastolic velocity of mitral flow (E)/Ea ratio (r=0.418, P=0.042). In multivariate stepwise linear regression analysis, EMAT was independently associated with AHI (P=0.025) and Ea (P=0.028) in OSA cases. Conclusion EMAT measured by TDI could be a useful parameter for identifying atrial remodeling in patients with severe OSA. (Circ J 2009; 73: 249 - 255) |
|---|---|
| AbstractList | Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the association between OSA and atrial remodeling has not been fully elucidated.
Atrial electromechanical activation time (EMAT) was investigated using tissue Doppler imaging (TDI) in men with severe OSA (n=24) and control subjects (n=24). The EMAT was determined as the time interval from the initiation of P-wave deflection until the peak of local lateral left atrial (LA) TDI signal. The early diastolic velocity of the mitral annulus (E(a)) and the EMAT were significantly lower and longer in OSA cases than in controls (E(a): 6.1+/-0.9 cm/s vs 7.3+/-1.5 cm/s, P=0.001; EMAT: 129.7+/-11.5 ms vs 118.5+/-12.3 ms, P=0.002). Among OSA cases, the apnea - hypopnea index (AHI) was significantly correlated with EMAT (r=0.660, P<0.001), E(a) (r=-0.609, P=0.002), LA dimension (r=0.486, P=0.016), and early diastolic velocity of mitral flow (E)/E(a) ratio (r=0.418, P=0.042). In multivariate stepwise linear regression analysis, EMAT was independently associated with AHI (P=0.025) and E(a) (P=0.028) in OSA cases.
EMAT measured by TDI could be a useful parameter for identifying atrial remodeling in patients with severe OSA. Background Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the association between OSA and atrial remodeling has not been fully elucidated. Methods and Results Atrial electromechanical activation time (EMAT) was investigated using tissue Doppler imaging (TDI) in men with severe OSA (n=24) and control subjects (n=24). The EMAT was determined as the time interval from the initiation of P-wave deflection until the peak of local lateral left atrial (LA) TDI signal. The early diastolic velocity of the mitral annulus (Ea) and the EMAT were significantly lower and longer in OSA cases than in controls (Ea: 6.1±0.9 cm/s vs 7.3±1.5 cm/s, P=0.001; EMAT: 129.7±11.5 ms vs 118.5±12.3 ms, P=0.002). Among OSA cases, the apnea - hypopnea index (AHI) was significantly correlated with EMAT (r=0.660, P<0.001), Ea (r=-0.609, P=0.002), LA dimension (r=0.486, P=0.016), and early diastolic velocity of mitral flow (E)/Ea ratio (r=0.418, P=0.042). In multivariate stepwise linear regression analysis, EMAT was independently associated with AHI (P=0.025) and Ea (P=0.028) in OSA cases. Conclusion EMAT measured by TDI could be a useful parameter for identifying atrial remodeling in patients with severe OSA. (Circ J 2009; 73: 249 - 255) Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the association between OSA and atrial remodeling has not been fully elucidated.BACKGROUNDObstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the association between OSA and atrial remodeling has not been fully elucidated.Atrial electromechanical activation time (EMAT) was investigated using tissue Doppler imaging (TDI) in men with severe OSA (n=24) and control subjects (n=24). The EMAT was determined as the time interval from the initiation of P-wave deflection until the peak of local lateral left atrial (LA) TDI signal. The early diastolic velocity of the mitral annulus (E(a)) and the EMAT were significantly lower and longer in OSA cases than in controls (E(a): 6.1+/-0.9 cm/s vs 7.3+/-1.5 cm/s, P=0.001; EMAT: 129.7+/-11.5 ms vs 118.5+/-12.3 ms, P=0.002). Among OSA cases, the apnea - hypopnea index (AHI) was significantly correlated with EMAT (r=0.660, P<0.001), E(a) (r=-0.609, P=0.002), LA dimension (r=0.486, P=0.016), and early diastolic velocity of mitral flow (E)/E(a) ratio (r=0.418, P=0.042). In multivariate stepwise linear regression analysis, EMAT was independently associated with AHI (P=0.025) and E(a) (P=0.028) in OSA cases.METHODS AND RESULTSAtrial electromechanical activation time (EMAT) was investigated using tissue Doppler imaging (TDI) in men with severe OSA (n=24) and control subjects (n=24). The EMAT was determined as the time interval from the initiation of P-wave deflection until the peak of local lateral left atrial (LA) TDI signal. The early diastolic velocity of the mitral annulus (E(a)) and the EMAT were significantly lower and longer in OSA cases than in controls (E(a): 6.1+/-0.9 cm/s vs 7.3+/-1.5 cm/s, P=0.001; EMAT: 129.7+/-11.5 ms vs 118.5+/-12.3 ms, P=0.002). Among OSA cases, the apnea - hypopnea index (AHI) was significantly correlated with EMAT (r=0.660, P<0.001), E(a) (r=-0.609, P=0.002), LA dimension (r=0.486, P=0.016), and early diastolic velocity of mitral flow (E)/E(a) ratio (r=0.418, P=0.042). In multivariate stepwise linear regression analysis, EMAT was independently associated with AHI (P=0.025) and E(a) (P=0.028) in OSA cases.EMAT measured by TDI could be a useful parameter for identifying atrial remodeling in patients with severe OSA.CONCLUSIONEMAT measured by TDI could be a useful parameter for identifying atrial remodeling in patients with severe OSA. |
| Author | Pak, Hui-Nam Kim, Yong Hyun Lim, Hong Euy Kim, Eung Ju Kim, Seong Hwan Kim, Young-Hoon Shin, Chol Baik, Inkyung |
| Author_xml | – sequence: 1 fullname: Kim, Young-Hoon organization: Division of Cardiology, Cardiovascular Center – sequence: 1 fullname: Kim, Eung Ju organization: Division of Cardiology, Cardiovascular Center – sequence: 1 fullname: Kim, Yong Hyun organization: Division of Cardiology, Cardiovascular Center – sequence: 1 fullname: Lim, Hong Euy organization: Division of Cardiology, Cardiovascular Center – sequence: 1 fullname: Shin, Chol organization: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine – sequence: 1 fullname: Kim, Seong Hwan organization: Division of Cardiology, Cardiovascular Center – sequence: 1 fullname: Pak, Hui-Nam organization: Division of Cardiology, Cardiovascular Center – sequence: 1 fullname: Baik, Inkyung organization: Department of Food and Nutrition, College of Natural Science, Kookmin University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19106459$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kMtLxDAQh4Morq-7J-nJWzVp0jY5LourLsIi6jmk06mbpS-TrOB_b_ehC4IQkiF83zDzOyWHbdciIZeM3rAk5bdgHSxvJrOYyuEwfkBOGBd5LGRCDzd1Fisp-Iicer-kNFE0VcdkxBSjmUjVCXl-bHoDIeqqaF744FYQ7CdGLzViH437Fk3UtVFYYDQOzpo6uqsRgusahIVpLQw_47Vigh24V9vgOTmqTO3xYveekbfp3evkIX6a3z9Oxk8xpIqHGGROq0SYMucyZypNjChRKJ5WKhMZJJkqirIAAQZhGDtnw05QFWXKpeSsFPyMXG_79q77WKEPurEesK5Ni93K6yyTQjDGBvBqB66KBkvdO9sY96V_QhiAbAuA67x3WGmwYbNQcMbWmlG9Tltv0taTmaZSr9MeRPpH_O39vzLdKksfzDv-CsYFCzXuhJzrZH3txT2wME5jy78BG1-caQ |
| CitedBy_id | crossref_primary_10_1183_09059180_00004513 crossref_primary_10_1016_j_ijcard_2016_12_120 crossref_primary_10_1253_circj_CJ_09_0562 crossref_primary_10_1016_j_ahj_2023_03_014 crossref_primary_10_1253_circj_CJ_09_0557 crossref_primary_10_1097_CRD_0b013e318223bd08 crossref_primary_10_1111_jcmm_13145 crossref_primary_10_4070_kcj_2015_45_6_479 crossref_primary_10_1097_MCP_0b013e3283328a80 crossref_primary_10_1111_j_1440_1843_2012_02157_x crossref_primary_10_1155_2013_621736 crossref_primary_10_1016_j_jelectrocard_2011_03_009 crossref_primary_10_20538_1682_0363_2021_2_102_112 |
| Cites_doi | 10.1016/0735-1097(93)90381-A 10.1161/01.CIR.0000068337.25994.21 10.1111/j.1540-8167.2007.00723.x 10.1183/09031936.00043306 10.1001/archinternmed.2007.8 10.1016/j.ahj.2004.04.029 10.1093/aje/154.1.50 10.1161/01.CIR.0000118216.84358.22 10.1097/01.hco.0000131538.55528.8f 10.1172/JCI118235 10.1016/0002-9149(86)90771-X 10.1161/01.CIR.0000136587.68725.8E 10.1161/CIRCULATIONAHA.107.727081 10.1016/S0002-8703(00)90048-6 10.1016/j.echo.2005.03.022 10.1097/00004872-200108000-00013 10.1164/rccm.200404-519OC 10.1016/S0735-1097(03)00464-9 10.1001/jama.292.20.2471 10.1016/S0008-6363(02)00258-4 10.1161/01.CIR.83.1.162 10.1016/S0002-9149(02)02864-3 10.1253/circj.70.737 10.1253/circj.71.1636 10.1111/j.1540-8159.2007.00700.x 10.1111/j.1540-8159.2007.00656.x 10.1016/j.amjcard.2006.12.052 10.1016/j.echo.2006.01.009 10.1253/circj.71.252 10.1378/chest.119.1.62 10.1016/j.jacc.2006.08.060 10.1164/rccm.200610-1527OC |
| ContentType | Journal Article |
| Copyright | 2009 THE JAPANESE CIRCULATION SOCIETY |
| Copyright_xml | – notice: 2009 THE JAPANESE CIRCULATION SOCIETY |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1253/circj.CJ-08-0813 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1347-4820 |
| EndPage | 255 |
| ExternalDocumentID | 19106459 10_1253_circj_CJ_08_0813 article_circj_73_2_73_CJ_08_0813_article_char_en |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- .55 .GJ 29B 2WC 3O- 53G 5GY 5RE 6J9 ACGFO ADBBV AENEX ALMA_UNASSIGNED_HOLDINGS BAWUL CS3 DIK DU5 E3Z EBS EJD F5P GX1 JSF JSH KQ8 OK1 OVT P2P RJT RNS RZJ TKC TR2 W2D X7M XSB ZXP AAYXX CITATION CGR CUY CVF ECM EIF M~E NPM RYR 7X8 |
| ID | FETCH-LOGICAL-c593t-c870f24ad73871952a4de4935f9646c269bbdbc4caec29071482cfbd538831d43 |
| ISSN | 1346-9843 |
| IngestDate | Fri Jul 11 07:51:45 EDT 2025 Sat Sep 28 08:40:05 EDT 2024 Thu Apr 24 22:59:16 EDT 2025 Tue Jul 01 02:00:54 EDT 2025 Wed Sep 03 06:29:56 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c593t-c870f24ad73871952a4de4935f9646c269bbdbc4caec29071482cfbd538831d43 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/circj/73/2/73_CJ-08-0813/_article/-char/en |
| PMID | 19106459 |
| PQID | 66844111 |
| PQPubID | 23479 |
| PageCount | 7 |
| ParticipantIDs | proquest_miscellaneous_66844111 pubmed_primary_19106459 crossref_citationtrail_10_1253_circj_CJ_08_0813 crossref_primary_10_1253_circj_CJ_08_0813 jstage_primary_article_circj_73_2_73_CJ_08_0813_article_char_en |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2009-00-00 |
| PublicationDateYYYYMMDD | 2009-01-01 |
| PublicationDate_xml | – year: 2009 text: 2009-00-00 |
| PublicationDecade | 2000 |
| PublicationPlace | Japan |
| PublicationPlace_xml | – name: Japan |
| PublicationTitle | Circulation Journal |
| PublicationTitleAlternate | Circ J |
| PublicationYear | 2009 |
| Publisher | The Japanese Circulation Society |
| Publisher_xml | – name: The Japanese Circulation Society |
| References | 10. Tang M, Zhang S, Sun Q, Huang C. Alterations in electrophysiology and tissue structure of the left atrial posterior wall in a canine model of atrial fibrillation caused by chronic atrial dilatation. Circ J 2007; 71: 1636-1642. 19. Tsang TS, Barnes ME, Gersh BJ, Bailey KR, Seward JB. Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol 2002; 90: 1284-1289. 29. Otto ME, Belohlavek M, Romero-Corral A, Gami AS, Gilman G, Svatikova A, et al. Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apnea. Am J Cardiol 2007; 99: 1298-1302. 1. Quan SF, Gersh BJ. Cardiovascular consequences of sleep-disordered breathing: Past, present and future: Report of a workshop from the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute. Circulation 2004; 109: 951-957. 15. Parkash R, Green MS, Kerr CR, Connolly SJ, Klein GJ, Sheldon R, et al. The association of left atrial size and occurrence of atrial fibrillation: A prospective cohort study from the Canadian Registry of Atrial Fibrillation. Am Heart J 2004; 148: 649-654. 24. Allessie M, Ausma J, Schotten U. Electrical, contractile and structural remodeling during atrial fibrillation. Cardiovasc Res 2002; 54: 230-246. 17. Peterson LR, Waggoner AD, de las Fuentes L, Schechtman KB, McGill JB, Gropler RJ, et al. Alterations in left ventricular structure and function in type-1 diabetics: A focus on left atrial contribution to function. J Am Soc Echocardiogr 2006; 19: 749-755. 9. Kanagala R, Murali NS, Friedman PA, Ammash NM, Gersh BJ, Ballman KV, et al. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation 2003; 107: 2589-2594. 12. Baik I, Kim J, Abbott RD, Joo S, Jung K, Lee S, et al. Association of snoring with chronic bronchitis. Arch Intern Med 2008; 168: 167-173. 28. Merckx KL, De Vos CB, Palmans A, Habets J, Cheriex EC, Crijns HJ, et al. Atrial activation time determined by transthoracic Doppler tissue imaging can be used as an estimate of the total duration of atrial electrical activation. J Am Soc Echocardiogr 2005; 18: 940-944. 11. Roshanali F, Mandegar MH, Yousefnia MA, Rayatzadeh H, Alaeddini F, Amouzadeh F. Prediction of atrial fibrillation via atrial electromechanical interval after coronary artery bypass grafting. Circulation 2007; 116: 2012-2017. 23. Ishimoto N, Ito M, Kinoshita M. Signal-averaged P-wave abnormalities and atrial size in patients with and without idiopathic paroxysmal atrial fibrillation. Am Heart J 2000; 139: 684-689. 20. Wang TJ, Parise H, Levy D, D'Agostino RB Sr, Wolf PA, Vasan RS, et al. Obesity and the risk of new-onset atrial fibrillation. JAMA 2004; 292: 2471-2477. 21. Fukunami M, Yamada T, Ohmori M, Kumagai K, Umemoto K, Sakai A, et al. Detection of patients at risk for paroxysmal atrial fibrillation during sinus rhythm by P wave-triggered signal-averaged electrocardiogram. Circulation 1991; 83: 162-169. 18. Umetani K, Kodama Y, Nakamura T, Mende A, Kitta Y, Kawabata K, et al. High prevalence of paroxysmal atrial fibrillation and/or atrial flutter in metabolic syndrome. Circ J 2007; 71: 252-255. 14. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings. Am J Cardiol 1986; 57: 450-458. 16. Dokainish H. Tissue Doppler imaging in the evaluation of left ventricular diastolic function. Curr Opin Cardiol 2004; 19: 437-441. 6. von Kanel R, Le DT, Nelesen RA, Mills PJ, Ancoli-Israel S, Dimsdale JE. The hypercoagulable state in sleep apnea is related to comorbid hypertension. J Hypertens 2001; 19: 1445-1451. 32. Kumagai K, Nakashima H, Urata H, Gondo N, Arakawa K, Saku K. Effects of angiotensin II type 1 receptor antagonist on electrical and structural remodeling in atrial fibrillation. J Am Coll Cardiol 2003; 41: 2197-2204. 4. Tanriverdi H, Evrengul H, Kaftan A, Kara CO, Kuru O, Tanriverdi S, et al. Effect of obstructive sleep apnea on aortic elastic parameters: Relationship to left ventricular mass and function. Circ J 2006; 70: 737-743. 31. Ip MS, Lam B, Lauder IJ, Tsang KW, Chung KF, Mok YW, et al. A community study of sleep-disordered breathing in middle-aged Chinese men in Hong Kong. Chest 2001; 119: 62-69. 7. Gami AS, Hodge DO, Herges RM, Olson EJ, Nykodym J, Kara T, et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation. J Am Coll Cardiol 2007; 49: 565-571. 3. Iiyori N, Alonso LC, Li J, Sanders MH, Garcia-Ocana A, O'Doherty RM, et al. Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity. Am J Respir Crit Care Med 2007; 175: 851-857. 8. Gami AS, Pressman G, Caples SM, Kanagala R, Gard JJ, Davison DE, et al. Association of atrial fibrillation and obstructive sleep apnea. Circulation 2004; 110: 364-367. 5. Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995; 96: 1897-1904. 13. Kim J, In K, You S, Kang K, Shim J, Lee S, et al. Prevalence of sleep-disordered breathing in middle-aged Korean men and women. Am J Respir Crit Care Med 2004; 170: 1108-1113. 25. Kojodjojo P, Peters NS, Davies DW, Kanagaratnam P. Characterization of the electroanatomical substrate in human atrial fibrillation: The relationship between changes in atrial volume, refractoriness, wavefront propagation velocities, and AF burden. J Cardiovasc Electrophysiol 2007; 18: 269-275. 26. Budeus M, Felix O, Hennersdorf M, Wieneke H, Erbel R, Sack S. Prediction of conversion from paroxysmal to permanent atrial fibrillation. Pacing Clin Electrophysiol 2007; 30: 243-252. 2. Coughlin SR, Mawdsley L, Mugarza JA, Wilding JP, Calverley PM. Cardiovascular and metabolic effects of CPAP in obese males with OSA. Eur Respir J 2007; 29: 720-727. 22. Guidera SA, Steinberg JS. The signal-averaged P wave duration: A rapid and noninvasive marker of risk of atrial fibrillation. J Am Coll Cardiol 1993; 21: 1645-1651. 27. Chalfoun N, Harnick D, Pe E, Undavia M, Mehta D, Gomes JA. Reverse electrical remodeling of the atria post cardioversion in patients who remain in sinus rhythm assessed by signal averaging of the P-wave. Pacing Clin Electrophysiol 2007; 30: 502-509. 30. Newman AB, Nieto FJ, Guidry U, Lind BK, Redline S, Pickering TG, et al. Relation of sleep-disordered breathing to cardiovascular disease risk factors: The Sleep Heart Health Study. Am J Epidemiol 2001; 154: 50-59. 22 23 24 25 26 27 28 29 30 31 10 32 11 12 13 14 15 16 17 18 19 1 2 3 4 5 6 7 8 9 20 21 |
| References_xml | – reference: 28. Merckx KL, De Vos CB, Palmans A, Habets J, Cheriex EC, Crijns HJ, et al. Atrial activation time determined by transthoracic Doppler tissue imaging can be used as an estimate of the total duration of atrial electrical activation. J Am Soc Echocardiogr 2005; 18: 940-944. – reference: 21. Fukunami M, Yamada T, Ohmori M, Kumagai K, Umemoto K, Sakai A, et al. Detection of patients at risk for paroxysmal atrial fibrillation during sinus rhythm by P wave-triggered signal-averaged electrocardiogram. Circulation 1991; 83: 162-169. – reference: 16. Dokainish H. Tissue Doppler imaging in the evaluation of left ventricular diastolic function. Curr Opin Cardiol 2004; 19: 437-441. – reference: 22. Guidera SA, Steinberg JS. The signal-averaged P wave duration: A rapid and noninvasive marker of risk of atrial fibrillation. J Am Coll Cardiol 1993; 21: 1645-1651. – reference: 25. Kojodjojo P, Peters NS, Davies DW, Kanagaratnam P. Characterization of the electroanatomical substrate in human atrial fibrillation: The relationship between changes in atrial volume, refractoriness, wavefront propagation velocities, and AF burden. J Cardiovasc Electrophysiol 2007; 18: 269-275. – reference: 8. Gami AS, Pressman G, Caples SM, Kanagala R, Gard JJ, Davison DE, et al. Association of atrial fibrillation and obstructive sleep apnea. Circulation 2004; 110: 364-367. – reference: 3. Iiyori N, Alonso LC, Li J, Sanders MH, Garcia-Ocana A, O'Doherty RM, et al. Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity. Am J Respir Crit Care Med 2007; 175: 851-857. – reference: 23. Ishimoto N, Ito M, Kinoshita M. Signal-averaged P-wave abnormalities and atrial size in patients with and without idiopathic paroxysmal atrial fibrillation. Am Heart J 2000; 139: 684-689. – reference: 12. Baik I, Kim J, Abbott RD, Joo S, Jung K, Lee S, et al. Association of snoring with chronic bronchitis. Arch Intern Med 2008; 168: 167-173. – reference: 29. Otto ME, Belohlavek M, Romero-Corral A, Gami AS, Gilman G, Svatikova A, et al. Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apnea. Am J Cardiol 2007; 99: 1298-1302. – reference: 17. Peterson LR, Waggoner AD, de las Fuentes L, Schechtman KB, McGill JB, Gropler RJ, et al. Alterations in left ventricular structure and function in type-1 diabetics: A focus on left atrial contribution to function. J Am Soc Echocardiogr 2006; 19: 749-755. – reference: 20. Wang TJ, Parise H, Levy D, D'Agostino RB Sr, Wolf PA, Vasan RS, et al. Obesity and the risk of new-onset atrial fibrillation. JAMA 2004; 292: 2471-2477. – reference: 2. Coughlin SR, Mawdsley L, Mugarza JA, Wilding JP, Calverley PM. Cardiovascular and metabolic effects of CPAP in obese males with OSA. Eur Respir J 2007; 29: 720-727. – reference: 15. Parkash R, Green MS, Kerr CR, Connolly SJ, Klein GJ, Sheldon R, et al. The association of left atrial size and occurrence of atrial fibrillation: A prospective cohort study from the Canadian Registry of Atrial Fibrillation. Am Heart J 2004; 148: 649-654. – reference: 5. Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995; 96: 1897-1904. – reference: 19. Tsang TS, Barnes ME, Gersh BJ, Bailey KR, Seward JB. Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol 2002; 90: 1284-1289. – reference: 1. Quan SF, Gersh BJ. Cardiovascular consequences of sleep-disordered breathing: Past, present and future: Report of a workshop from the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute. Circulation 2004; 109: 951-957. – reference: 7. Gami AS, Hodge DO, Herges RM, Olson EJ, Nykodym J, Kara T, et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation. J Am Coll Cardiol 2007; 49: 565-571. – reference: 10. Tang M, Zhang S, Sun Q, Huang C. Alterations in electrophysiology and tissue structure of the left atrial posterior wall in a canine model of atrial fibrillation caused by chronic atrial dilatation. Circ J 2007; 71: 1636-1642. – reference: 27. Chalfoun N, Harnick D, Pe E, Undavia M, Mehta D, Gomes JA. Reverse electrical remodeling of the atria post cardioversion in patients who remain in sinus rhythm assessed by signal averaging of the P-wave. Pacing Clin Electrophysiol 2007; 30: 502-509. – reference: 26. Budeus M, Felix O, Hennersdorf M, Wieneke H, Erbel R, Sack S. Prediction of conversion from paroxysmal to permanent atrial fibrillation. Pacing Clin Electrophysiol 2007; 30: 243-252. – reference: 9. Kanagala R, Murali NS, Friedman PA, Ammash NM, Gersh BJ, Ballman KV, et al. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation 2003; 107: 2589-2594. – reference: 13. Kim J, In K, You S, Kang K, Shim J, Lee S, et al. Prevalence of sleep-disordered breathing in middle-aged Korean men and women. Am J Respir Crit Care Med 2004; 170: 1108-1113. – reference: 32. Kumagai K, Nakashima H, Urata H, Gondo N, Arakawa K, Saku K. Effects of angiotensin II type 1 receptor antagonist on electrical and structural remodeling in atrial fibrillation. J Am Coll Cardiol 2003; 41: 2197-2204. – reference: 31. Ip MS, Lam B, Lauder IJ, Tsang KW, Chung KF, Mok YW, et al. A community study of sleep-disordered breathing in middle-aged Chinese men in Hong Kong. Chest 2001; 119: 62-69. – reference: 4. Tanriverdi H, Evrengul H, Kaftan A, Kara CO, Kuru O, Tanriverdi S, et al. Effect of obstructive sleep apnea on aortic elastic parameters: Relationship to left ventricular mass and function. Circ J 2006; 70: 737-743. – reference: 24. Allessie M, Ausma J, Schotten U. Electrical, contractile and structural remodeling during atrial fibrillation. Cardiovasc Res 2002; 54: 230-246. – reference: 6. von Kanel R, Le DT, Nelesen RA, Mills PJ, Ancoli-Israel S, Dimsdale JE. The hypercoagulable state in sleep apnea is related to comorbid hypertension. J Hypertens 2001; 19: 1445-1451. – reference: 18. Umetani K, Kodama Y, Nakamura T, Mende A, Kitta Y, Kawabata K, et al. High prevalence of paroxysmal atrial fibrillation and/or atrial flutter in metabolic syndrome. Circ J 2007; 71: 252-255. – reference: 11. Roshanali F, Mandegar MH, Yousefnia MA, Rayatzadeh H, Alaeddini F, Amouzadeh F. Prediction of atrial fibrillation via atrial electromechanical interval after coronary artery bypass grafting. Circulation 2007; 116: 2012-2017. – reference: 30. Newman AB, Nieto FJ, Guidry U, Lind BK, Redline S, Pickering TG, et al. Relation of sleep-disordered breathing to cardiovascular disease risk factors: The Sleep Heart Health Study. Am J Epidemiol 2001; 154: 50-59. – reference: 14. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings. Am J Cardiol 1986; 57: 450-458. – ident: 22 doi: 10.1016/0735-1097(93)90381-A – ident: 9 doi: 10.1161/01.CIR.0000068337.25994.21 – ident: 25 doi: 10.1111/j.1540-8167.2007.00723.x – ident: 2 doi: 10.1183/09031936.00043306 – ident: 12 doi: 10.1001/archinternmed.2007.8 – ident: 15 doi: 10.1016/j.ahj.2004.04.029 – ident: 30 doi: 10.1093/aje/154.1.50 – ident: 1 doi: 10.1161/01.CIR.0000118216.84358.22 – ident: 16 doi: 10.1097/01.hco.0000131538.55528.8f – ident: 5 doi: 10.1172/JCI118235 – ident: 14 doi: 10.1016/0002-9149(86)90771-X – ident: 8 doi: 10.1161/01.CIR.0000136587.68725.8E – ident: 11 doi: 10.1161/CIRCULATIONAHA.107.727081 – ident: 23 doi: 10.1016/S0002-8703(00)90048-6 – ident: 28 doi: 10.1016/j.echo.2005.03.022 – ident: 6 doi: 10.1097/00004872-200108000-00013 – ident: 13 doi: 10.1164/rccm.200404-519OC – ident: 32 doi: 10.1016/S0735-1097(03)00464-9 – ident: 20 doi: 10.1001/jama.292.20.2471 – ident: 24 doi: 10.1016/S0008-6363(02)00258-4 – ident: 21 doi: 10.1161/01.CIR.83.1.162 – ident: 19 doi: 10.1016/S0002-9149(02)02864-3 – ident: 4 doi: 10.1253/circj.70.737 – ident: 10 doi: 10.1253/circj.71.1636 – ident: 27 doi: 10.1111/j.1540-8159.2007.00700.x – ident: 26 doi: 10.1111/j.1540-8159.2007.00656.x – ident: 29 doi: 10.1016/j.amjcard.2006.12.052 – ident: 17 doi: 10.1016/j.echo.2006.01.009 – ident: 18 doi: 10.1253/circj.71.252 – ident: 31 doi: 10.1378/chest.119.1.62 – ident: 7 doi: 10.1016/j.jacc.2006.08.060 – ident: 3 doi: 10.1164/rccm.200610-1527OC |
| SSID | ssj0029059 |
| Score | 1.9446048 |
| Snippet | Background Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However,... Obstructive sleep apnea (OSA) is closely associated with atrial fibrillation, which is provoked by electrical and structural remodeling. However, the... |
| SourceID | proquest pubmed crossref jstage |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 249 |
| SubjectTerms | Adult Aged Apnea - hypopnea index Atrial remodeling Blood Pressure - physiology Case-Control Studies Echocardiography Heart Atria - diagnostic imaging Heart Atria - physiopathology Heart Conduction System - physiopathology Heart Ventricles - physiopathology Humans Linear Models Male Middle Aged Obstructive sleep apnea Polysomnography Sleep Apnea, Obstructive - physiopathology Tissue Doppler imaging |
| Title | Impact of Obstructive Sleep Apnea on the Atrial Electromechanical Activation Time |
| URI | https://www.jstage.jst.go.jp/article/circj/73/2/73_CJ-08-0813/_article/-char/en https://www.ncbi.nlm.nih.gov/pubmed/19106459 https://www.proquest.com/docview/66844111 |
| Volume | 73 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | Circulation Journal, 2009, Vol.73(2), pp.249-255 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELaWglAviDfL0wcuKErbdRwnPiG0WlgiFQnRSsspchynULXJqt0UwZU_zvgRJ92yCLhYkR9xMjMZz8Tj-RB6mXBWcqG33YnaC6nkZci5KMK4mjAhJE9LpQ8n739g80OaLeLFaPRzELXUrood-eO350r-h6tQB3zVp2T_gbP-plAB18BfKIHDUP4Vj9_7I45N4RLBXqjg_ESpZSCWtRJuKyAQFpzDYd6cKn3c16YJkB28mUGZH5qq069n0mF7-fwSm5JO6DkyWHY1nGUwHOiCQn3Yj8VunmuAo1nrqx2k82ddPf_e1mv1n5Rp-CbWG2agqYKsvfTngg_UbERZyFOboKnTwxbSxMkbGSpVm9T0irInBrFDwksd70wzE5WX2oOtA94vTw3zwS3Vmfl4v-z5YMSu6Rq6TpJkouNC3y18nBDhewZxzz-y2-uGyXfXpzYZaO3NLpk5N47B0j9Sm50YY8wc3Ea3nBeC31iRuoNGqr6Lbu67OIt76KOVLNxUeCBZ2EgWNpKFmxoD17GVLHxFsnAvWVhL1n10-HZ2MJ2HDnwjlDGPVqEERV4RKsokAp-ax0TQUlEexRVnlEnCeFGUhaRSKAk0SnQ-WVkVJSygaTQpafQAbdVNrR4hHMlIgaYgZUXBXmUMiAh2t0oLcBZiuO0Y7Xa0yqXLTK8BUk5y7aECoXND6Hya5RoyFQg9Rq_8iKXNyvKHvq8t-X1P9726nkmUE130I_oOX8QZ6JkxetHxLQflq3fU4Htq2vNcvwsFa2GMHlp29k_j5ODxxpYnaNvuTOrfeU_RFvBSPQMDd1U8NwL4C30RqO8 |
| linkProvider | Geneva Foundation for Medical Education and Research |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Impact+of+obstructive+sleep+apnea+on+the+atrial+electromechanical+activation+time&rft.jtitle=Circulation+journal+%3A+official+journal+of+the+Japanese+Circulation+Society&rft.au=Lim%2C+Hong+Euy&rft.au=Kim%2C+Yong+Hyun&rft.au=Kim%2C+Seong+Hwan&rft.au=Kim%2C+Eung+Ju&rft.date=2009&rft.issn=1346-9843&rft.volume=73&rft.issue=2&rft.spage=249&rft_id=info:doi/10.1253%2Fcircj.CJ-08-0813&rft_id=info%3Apmid%2F19106459&rft.externalDocID=19106459 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1346-9843&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1346-9843&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1346-9843&client=summon |