Prospective study of pandysmaturation and adult mental disorder in high-risk and normal-risk offspring

• Published in: Journal of psychiatric research Vol. 45; no. 4; pp. 561 - 567
• Main Authors: McNeil, Thomas F, Fish, Barbara, Schubert, Erland W
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.04.2011; Elsevier
• Subjects: Adult; Adult and adolescent clinical studies; Affective disorder; Biological and medical sciences; Child; Child of Impaired Parents - psychology; Clinical Medicine; Cognition - physiology; Developmental Disabilities - epidemiology; Developmental Disabilities - etiology; Female; Fish; Genetic susceptibility; High risk; Humans; Klinisk medicin; Logistic Models; Male; Medical and Health Sciences; Medical sciences; Medicin och hälsovetenskap; Mental Disorders - diagnosis; Mental Disorders - epidemiology; Mental Disorders - etiology; Mental Disorders - genetics; Neurodevelopment; Obstetric Labor Complications - physiopathology; Odds Ratio; Pandysmaturation; Pregnancy; Prospective Studies; Psychiatric Status Rating Scales; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Psykiatri; Risk Factors; Risk group; Schizophrenia; Social Behavior; Young Adult; Young adulthood; Affective disorder; Schizophrenia; Neurodevelopment; Pandysmaturation; Risk group; Human; Mood disorder; High risk; Psychosis; Progeny; Follow up study; Mental disorder; Adult

Abstract More than 50 years ago, Fish postulated that a special form of early abnormal neurodevelopment, “pandysmaturation”, defined a priori as constituting retarded cranial development in the first year of life, combined with delay in early motor milestone attainment, was related to genetic risk f...