Eculizumab in patients with severe coronavirus disease 2019 (COVID-19) requiring continuous positive airway pressure ventilator support: Retrospective cohort study - Ruggenenti, Piero; Di Marco, Fabiano; Cortinovis, Monica; Lorini, Luca; Sala, Silvia; Novelli, Luca; Raimondi, Federico; Gastoldi, Sara; Galbusera, Miriam; Donadelli, Roberta; Mele, Caterina; Piras, Rossella; et al. (PloS one, 2021)
Keywords: Aged; Antibodies, Monoclonal, Humanized - administration & dosage; Antibodies, Monoclonal, Humanized - therapeutic use; Biology and Life Sciences; Case-Control Studies; Clinical trials; Cohort analysis; Complement activation; Complement Membrane Attack Complex - analysis; Complications; Continuous Positive Airway Pressure; Coronaviruses; COVID-19; COVID-19 - drug therapy; COVID-19 - mortality; COVID-19 - physiopathology; COVID-19 - therapy; Creatinine; Drug dosages; Engineering and Technology; Female; Health aspects; Humans; Laboratories; Lung diseases; Male; Medicine and Health Sciences; Middle Aged; Monoclonal antibodies; Mortality; Respiration; Respiratory rate; Respiratory tract; Retrospective Studies; Thrombosis - drug therapy; Treatment Outcome; Viral diseases; Italy