MAUI (MBI Analysis User Interface)—An image processing pipeline for Multiplexed Mass Based Imaging

• Published in: PLoS computational biology Vol. 17; no. 4; p. e1008887
• Main Authors: Baranski, Alex, Milo, Idan, Greenbaum, Shirley, Oliveria, John-Paul, Mrdjen, Dunja, Angelo, Michael, Keren, Leeat
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.04.2021; Public Library of Science (PLoS)
• Subjects: Aggregates; Algorithms; Antibodies; Biology and Life Sciences; Charities; Computer and Information Sciences; Crosstalk; Defense programs; Grants; Graphical user interface; Image processing; Interfaces; Ion beams; Mass spectrometry; Methods; Noise; Parameters; Physical Sciences; Proteins; Research and Analysis Methods; Scientific imaging; Software; Stockholders; Subject specialists; Time-of-flight mass spectrometry; Tissues; User interface; User interfaces; Italy

Mass Based Imaging (MBI) technologies such as Multiplexed Ion Beam Imaging by time of flight (MIBI-TOF) and Imaging Mass Cytometry (IMC) allow for the simultaneous measurement of the expression levels of 40 or more proteins in biological tissue, providing insight into cellular phenotypes and organiz...