Intestinal microbiota mediates Enterotoxigenic Escherichia coli-induced diarrhea in piglets

• Published in: BMC veterinary research Vol. 14; no. 1; p. 385
• Main Authors: Bin, Peng, Tang, Zhiyi, Liu, Shaojuan, Chen, Shuai, Xia, Yaoyao, Liu, Jiaqi, Wu, Hucong, Zhu, Guoqiang
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.12.2018; BioMed Central; BMC
• Subjects: Bacteria; Care and treatment; Communicable diseases; Complications and side effects; cows; Development and progression; Diarrhea; Digestive system; Dysbacteriosis; dysbiosis; E coli; Enterotoxigenic Escherichia coli; Escherichia coli; Escherichia coli infections; Experiments; Fecal microflora; Feces; Gastrointestinal tract; Health aspects; Hogs; Host-bacteria relationships; humans; Immune response; Infections; Infectious diseases; Intestinal microflora; intestinal microorganisms; Intestine; Jejunum; Lactococcus; Mediation; Metabolites; metagenomics; Microbiota; Microbiota (Symbiotic organisms); Microbiota transplantation; Pathogenesis; Physiology; Piglet; piglets; Prevotella; ribosomal RNA; RNA; rRNA 16S; sequence analysis; Structure-function relationships; Surgery; Swine; Transplantation; Type 2 diabetes; veterinary medicine; China; Diarrhea; Microbiota transplantation; Microbiota; Piglet; Enterotoxigenic Escherichia coli

Enterotoxigenic Escherichia coli (ETEC) causes diarrhea in humans, cows, and pigs. The gut microbiota underlies pathology of several infectious diseases yet the role of the gut microbiota in the pathogenesis of ETEC-induced diarrhea is unknown. By using an ETEC induced diarrheal model in piglet, we...