Impact of mental disorders and chronic physical conditions on quality-adjusted life years in Singapore

The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and chronic physical conditions. The second Singapore Mental Health Study (SMHS-2016) was conducted in 2016 among 6126 respondents aged 18 years an...

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Published inScientific reports Vol. 10; no. 1; p. 2695
Main Authors Abdin, Edimansyah, Chong, Siow Ann, Vaingankar, Janhavi Ajit, Shafie, Saleha, Verma, Swapna, Luo, Nan, Tan, Kelvin Bryan, James, Lyn, Heng, Derrick, Subramaniam, Mythily
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Published London Nature Publishing Group UK 14.02.2020
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Abstract The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and chronic physical conditions. The second Singapore Mental Health Study (SMHS-2016) was conducted in 2016 among 6126 respondents aged 18 years and above. The World Health Organization Composite International Diagnostic Interview version 3.0 (WHO-CIDI 3.0) and a modified version of the CIDI chronic medical disorders checklist were used to assess the 12-month diagnoses of mental and chronic physical disorders while the SF-6D scores derived from the 12-item Short Form Health Survey instrument was used to estimate the QALYs lost. The mean SF-6D score in this population was 0.87. The largest reduction in SF-6D scores among people with mental disorders was observed in Generalized Anxiety Disorder (GAD), followed by Major Depressive Disorder (MDD), alcohol abuse, bipolar disorder and Obsessive Compulsive Disorder (OCD) while the largest reduction in SF-6D score among people with chronic physical conditions was observed in ulcer, followed by lung disease, chronic pain and cardiovascular disease. At the population level, chronic pain was associated with the greatest QALY loss followed by MDD (14,204 and 6,889 respectively). Lung disease was associated with the smallest QALY loss (376). These findings highlight chronic pain, MDD, OCD, cardiovascular disease and GAD as the five leading contributors of QALYs lost in the general population which deserve prioritisation in public health prevention programmes.
AbstractList The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and chronic physical conditions. The second Singapore Mental Health Study (SMHS-2016) was conducted in 2016 among 6126 respondents aged 18 years and above. The World Health Organization Composite International Diagnostic Interview version 3.0 (WHO-CIDI 3.0) and a modified version of the CIDI chronic medical disorders checklist were used to assess the 12-month diagnoses of mental and chronic physical disorders while the SF-6D scores derived from the 12-item Short Form Health Survey instrument was used to estimate the QALYs lost. The mean SF-6D score in this population was 0.87. The largest reduction in SF-6D scores among people with mental disorders was observed in Generalized Anxiety Disorder (GAD), followed by Major Depressive Disorder (MDD), alcohol abuse, bipolar disorder and Obsessive Compulsive Disorder (OCD) while the largest reduction in SF-6D score among people with chronic physical conditions was observed in ulcer, followed by lung disease, chronic pain and cardiovascular disease. At the population level, chronic pain was associated with the greatest QALY loss followed by MDD (14,204 and 6,889 respectively). Lung disease was associated with the smallest QALY loss (376). These findings highlight chronic pain, MDD, OCD, cardiovascular disease and GAD as the five leading contributors of QALYs lost in the general population which deserve prioritisation in public health prevention programmes.
The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and chronic physical conditions. The second Singapore Mental Health Study (SMHS-2016) was conducted in 2016 among 6126 respondents aged 18 years and above. The World Health Organization Composite International Diagnostic Interview version 3.0 (WHO-CIDI 3.0) and a modified version of the CIDI chronic medical disorders checklist were used to assess the 12-month diagnoses of mental and chronic physical disorders while the SF-6D scores derived from the 12-item Short Form Health Survey instrument was used to estimate the QALYs lost. The mean SF-6D score in this population was 0.87. The largest reduction in SF-6D scores among people with mental disorders was observed in Generalized Anxiety Disorder (GAD), followed by Major Depressive Disorder (MDD), alcohol abuse, bipolar disorder and Obsessive Compulsive Disorder (OCD) while the largest reduction in SF-6D score among people with chronic physical conditions was observed in ulcer, followed by lung disease, chronic pain and cardiovascular disease. At the population level, chronic pain was associated with the greatest QALY loss followed by MDD (14,204 and 6,889 respectively). Lung disease was associated with the smallest QALY loss (376). These findings highlight chronic pain, MDD, OCD, cardiovascular disease and GAD as the five leading contributors of QALYs lost in the general population which deserve prioritisation in public health prevention programmes.
ArticleNumber 2695
Author Heng, Derrick
Subramaniam, Mythily
Chong, Siow Ann
Tan, Kelvin Bryan
Luo, Nan
Vaingankar, Janhavi Ajit
Verma, Swapna
Abdin, Edimansyah
Shafie, Saleha
James, Lyn
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Snippet The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and...
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SubjectTerms 692/699/476/1300
692/699/476/1414
692/699/476/4032
692/700/478/174
692/700/784
Abuse
Adolescent
Adult
Aged
Aged, 80 and over
Alcohol abuse
Anxiety
Anxiety - epidemiology
Bipolar disorder
Cardiovascular disease
Cardiovascular diseases
Chronic pain
Depression - epidemiology
Drug abuse
Female
Humanities and Social Sciences
Humans
Lung diseases
Male
Mental depression
Mental disorders
Mental Disorders - epidemiology
Mental Disorders - pathology
Middle Aged
multidisciplinary
Multiple Chronic Conditions - epidemiology
Obsessive compulsive disorder
Obsessive-Compulsive Disorder - epidemiology
Pain
Public health
Quality-Adjusted Life Years
Science
Science (multidisciplinary)
Singapore - epidemiology
Young Adult
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Title Impact of mental disorders and chronic physical conditions on quality-adjusted life years in Singapore
URI https://link.springer.com/article/10.1038/s41598-020-59604-0
https://www.ncbi.nlm.nih.gov/pubmed/32060390
https://www.proquest.com/docview/2355270387
https://search.proquest.com/docview/2355937192
https://pubmed.ncbi.nlm.nih.gov/PMC7021810
Volume 10
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