Combination Biologic Therapy with Mepolizumab and Dupilumab for Severe Eosinophilic Granulomatosis with Polyangiitis and Chronic Rhinosinusitis with Nasal Polyp

• Published in: Yonago acta medica Vol. 67; no. 2; pp. 157 - 162
• Main Authors: Nakamura, Yosuke, Kikumoto, Naoki, Takeuchi, Hiromi, Kimura, Toru, Nakamori, Motoki, Fujiwara, Kazunori
• Format: Journal Article
• Language: English
• Published: Japan YAM 01.05.2024
• Subjects: Patient Report; combination therapy; eosinophilic granulomatosis with polyangiitis; asthma; biologic therapy; rhinosinusitis

We report the case of a 55-year-old female with eosinophilic granulomatosis with polyangiitis and chronic rhinosinusitis with nasal polyp. Rhinosinusitis recurred 6 months after full-house endoscopic sinus surgery. Although conventional treatment with azathioprine and mepolizumab with steroids was g...