Pressure effects on lipids and bio-membrane assemblies

Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in probing the structure and dynamics of membrane assembl...

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Published inIUCrJ Vol. 1; no. Pt 6; pp. 470 - 477
Main Author Brooks, Nicholas J
Format Journal Article
LanguageEnglish
Published England International Union of Crystallography 01.11.2014
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Abstract Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea organisms. This article presents an overview of the effect of pressure on the mesostructure of lipid membranes, bilayer organization and lipid-protein assemblies. It also summarizes recent developments in high-pressure structural instrumentation suitable for experiments on membranes.
AbstractList Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea organisms. This article presents an overview of the effect of pressure on the mesostructure of lipid membranes, bilayer organization and lipid-protein assemblies. It also summarizes recent developments in high-pressure structural instrumentation suitable for experiments on membranes.
Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea organisms. This article presents an overview of the effect of pressure on the mesostructure of lipid membranes, bilayer organization and lipid-protein assemblies. It also summarizes recent developments in high-pressure structural instrumentation suitable for experiments on membranes. Keywords: biological membranes; lipids; bilayers; lipid-protein assemblies; high-pressure studies
Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea organisms. This article presents an overview of the effect of pressure on the structure of membranes and recent developments in high-pressure instrumentation. Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea organisms. This article presents an overview of the effect of pressure on the mesostructure of lipid membranes, bilayer organization and lipid–protein assemblies. It also summarizes recent developments in high-pressure structural instrumentation suitable for experiments on membranes.
Audience Academic
Author Brooks, Nicholas J
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Nicholas J. Brooks 2014 2014
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Issue Pt 6
Keywords lipid–protein assemblies
lipids
bilayers
biological membranes
high-pressure studies
Language English
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Snippet Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play...
Pressure can play a key role in probing the structure and dynamics of membrane assemblies, and is also critical to the biology and adaptation of deep-sea...
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SubjectTerms Adaptation
Assemblies
bilayers
biological membranes
Biology
Health aspects
high-pressure studies
Identification and classification
Instrumentation
Integrity
Lipid metabolism
Lipids
lipid–protein assemblies
Membranes
Membranes (Biology)
Organisms
Pressure
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Title Pressure effects on lipids and bio-membrane assemblies
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