Daily Intake of Cod or Salmon for 2 Weeks Decreases the 18:1n-9/18:0 Ratio and Serum Triacylglycerols in Healthy Subjects

• Published in: Lipids Vol. 47; no. 2; pp. 151 - 160
• Main Authors: Telle-Hansen, Vibeke H., Larsen, Laila N., Høstmark, Arne T., Molin, Marianne, Dahl, Lisbeth, Almendingen, Kari, Ulven, Stine M.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.02.2012; Springer‐Verlag; Springer Nature B.V
• Subjects: 18:1n‐9/18:0 ratio; Adult; Animals; Biomedical and Life Sciences; blood serum; cod (fish); Diet; docosahexaenoic acid; eicosapentaenoic acid; fatty acid composition; Fatty Acid Synthases - genetics; Fatty Acid Synthases - metabolism; Fatty acids; Fatty Acids, Omega-3 - metabolism; fatty fish; fatty-acid synthase; Female; females; Fish; fish consumption; Gadiformes; Gene expression; Humans; Leukocytes, Mononuclear - metabolism; Life Sciences; lipid metabolism; Lipidology; Male; males; Marine; Medical Biochemistry; Medicinal Chemistry; messenger RNA; Microbial Genetics and Genomics; mononuclear leukocytes; Neurochemistry; Nutrition; Omega 3; omega-3 fatty acids; Original Article; PBMC; phospholipids; Phospholipids - blood; potatoes; Salmon; Salmonidae; Seafood; Solanum tuberosum; stearoyl-CoA desaturase; Stearoyl-CoA Desaturase - genetics; Stearoyl-CoA Desaturase - metabolism; Triacylglycerols; Triglycerides - blood; Humans; Omega 3; Fish; Gene expression; PBMC; 18:1n-9/18:0 ratio; Triacylglycerols

Intake of fish and omega-3 (n-3) fatty acids is associated with a reduced concentration of plasma triacylglycerols (TAG) but the mechanisms are not fully clarified. Stearoyl-CoA desaturase-1 (SCD1) activity, governing TAG synthesis, is affected by n-3 fatty acids. Peripheral blood mononuclear cells...