EP方案同步放疗治疗局限期小细胞肺癌的临床研究

R730.55; 目的研究EP方案同步放疗治疗42例局限期小细胞肺癌的疗效及副反应.方法化疗采用EP方案:放疗为常规分割2Gy/次,每周5次,总剂量为54～60Gy.结果治疗过程中放射性肺炎发生率62%,其中Ⅲ级为7%; 急性放射性食管炎发生率为79%,Ⅲ～Ⅳ级为12%;粒细胞下降发生率为71%,Ⅲ～Ⅳ级为21%;中位生存期为23月,1、2、3年局部控制率分别为88%、79%、71%;1、2、3年生存率分别为86%、55%、24%.结论 EP方案同步放疗治疗局限期小细胞肺癌,患者可耐受,局部控制率和生存率有所改善,长期生存优势有待进一步观察....

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Published in肿瘤防治研究 Vol. 32; no. 8; pp. 517 - 518
Main Authors 胡德胜, 贺晓俊, 谭文勇, 魏来, 宋启斌
Format Journal Article
LanguageChinese
Published 430079,武汉,湖北省肿瘤医院放疗科 2005
Subjects
化学治疗
局限性小细胞肺癌
放射治疗
Online AccessGet full text
ISSN1000-8578
DOI10.3971/j.issn.1000-8578.2005.08.023

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Abstract R730.55; 目的研究EP方案同步放疗治疗42例局限期小细胞肺癌的疗效及副反应.方法化疗采用EP方案:放疗为常规分割2Gy/次,每周5次,总剂量为54～60Gy.结果治疗过程中放射性肺炎发生率62%,其中Ⅲ级为7%; 急性放射性食管炎发生率为79%,Ⅲ～Ⅳ级为12%;粒细胞下降发生率为71%,Ⅲ～Ⅳ级为21%;中位生存期为23月,1、2、3年局部控制率分别为88%、79%、71%;1、2、3年生存率分别为86%、55%、24%.结论 EP方案同步放疗治疗局限期小细胞肺癌,患者可耐受,局部控制率和生存率有所改善,长期生存优势有待进一步观察.
AbstractList R730.55; 目的研究EP方案同步放疗治疗42例局限期小细胞肺癌的疗效及副反应.方法化疗采用EP方案:放疗为常规分割2Gy/次,每周5次,总剂量为54～60Gy.结果治疗过程中放射性肺炎发生率62%,其中Ⅲ级为7%; 急性放射性食管炎发生率为79%,Ⅲ～Ⅳ级为12%;粒细胞下降发生率为71%,Ⅲ～Ⅳ级为21%;中位生存期为23月,1、2、3年局部控制率分别为88%、79%、71%;1、2、3年生存率分别为86%、55%、24%.结论 EP方案同步放疗治疗局限期小细胞肺癌,患者可耐受,局部控制率和生存率有所改善,长期生存优势有待进一步观察.
Author 胡德胜
宋启斌
魏来
谭文勇
贺晓俊
AuthorAffiliation 430079,武汉,湖北省肿瘤医院放疗科
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TAN Wen-yong
HU De-sheng
SONG Qi-bin
WEI Lai
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放射治疗
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Snippet R730.55; 目的研究EP方案同步放疗治疗42例局限期小细胞肺癌的疗效及副反应.方法化疗采用EP方案:放疗为常规分割2Gy/次,每周5次,总剂量为54～60Gy.结果治疗过程中放射性肺炎发生率62%,其中Ⅲ级为7%;...
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StartPage 517
Title EP方案同步放疗治疗局限期小细胞肺癌的临床研究
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