Type 1 Diabetes Duration Decreases Pulmonary Diffusing Capacity during Exercise

• Published in: Respiration Vol. 91; no. 2; pp. 164 - 170
• Main Authors: Lee, Michelle J., Coast, J. Richard, Hempleman, Steven C., Baldi, J. Christopher
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.02.2016
• Subjects: Adolescent; Adult; Age Factors; Basic Science Investigations; Cardiac output; Care and treatment; Case-Control Studies; Child; Complications and side effects; Diabetes; Diabetes Mellitus, Type 1 - physiopathology; Exercise; Exercise - physiology; Female; Humans; Male; Observations; Pulmonary Diffusing Capacity; Pulmonary ventilation; Respiration; Respiratory tract diseases; Risk factors; Type 1 diabetes; Young Adult; United States; Exercise; Cardiac output; Pulmonary diffusing capacity; Altitude; Type 1 diabetes mellitus

Background: Diabetes damages peripheral tissues; however, its effects on the lung are less known. Lung diffusing capacity (D LCO ) is influenced by alveolar-capillary membrane conductance (D M ) and pulmonary capillary blood volume (V C ), both of which are reduced in adults with type 1 diabetes (T1...