Downregulation of transforming growth factor, beta receptor 2 and Notch signaling pathway in human abdominal aortic aneurysm - Biros, Erik; Walker, Philip J.; Nataatmadja, Maria; West, Malcolm; Golledge, Jonathan (Atherosclerosis, 2012)
Keywords: Abdominal aortic aneurysm; aneurysm; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Abdominal - genetics; Aortic Aneurysm, Abdominal - pathology; atherosclerosis; Atherosclerosis (general aspects, experimental research); Basic Helix-Loop-Helix Transcription Factors; Basic Helix-Loop-Helix Transcription Factors - genetics; Biological and medical sciences; Biopsy; Blood and lymphatic vessels; Cardiology. Vascular system; Cardiovascular; Case-Control Studies; Diseases of the aorta; DNA Copy Number Variations; Down-Regulation; etiology; Exons; Fibrillin-1; Fibrillins; Gene Amplification; Gene Deletion; gene expression regulation; genes; Genetic aberrations; Genetic Predisposition to Disease; genetics; Haploinsufficiency; Humans; Marfan Syndrome; Marfan Syndrome - genetics; Medical sciences; Microfilament Proteins; Microfilament Proteins - genetics; Muscle Proteins; Muscle Proteins - genetics; Mutation; pathogenesis; pathology; patients; Protein Serine-Threonine Kinases; Protein-Serine-Threonine Kinases - genetics; Queensland; Real-Time Polymerase Chain Reaction; Receptor, Notch3; Receptors, Notch; Receptors, Notch - genetics; Receptors, Transforming Growth Factor beta; Receptors, Transforming Growth Factor beta - genetics; Repressor Proteins; Repressor Proteins - genetics; signal transduction; Signal Transduction - genetics; smooth muscle; transforming growth factor beta; Queensland; Marfan syndrome; Genetic aberrations; Abdominal aortic aneurysm; Human; Connective tissue disease; Skin disease; Elastic tissue disease; Transforming growth factor; Cardiovascular disease; Aortic aneurysm; Genetic disease; Vascular disease; Growth factor receptor; Systemic disease; Atherosclerosis