Complete Resolution of TAFRO Syndrome (Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis and Organomegaly) after Immunosuppressive Therapies using Corticosteroids and Cyclosporin A : A Case Report

• Published in: Journal of Clinical and Experimental Hematopathology Vol. 53; no. 1; pp. 95 - 99
• Main Authors: Inoue, Morihiro, Ankou, Mayuka, Hua, Jiang, Iwaki, Yasunobu, Hagihara, Masao, Ota, Yasunori
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society for Lymphoreticular Tissue Research 2013
• Subjects: Adrenal Cortex Hormones - therapeutic use; autoimmune disorder; Castleman Disease - drug therapy; Castleman Disease - pathology; Cyclosporine - therapeutic use; Edema - drug therapy; Female; Fever - drug therapy; Humans; Immunosuppressive Agents - therapeutic use; Middle Aged; multicentric Castleman's disease; thrombocytopenia

A 49-year-old woman with severe thrombocytopenia was admitted after an episode of syncope. She also had anemia, fever, pleural effusion and ascites, and multiple lymphadenopathies subsequently appeared. Her bone marrow showed increased megakaryocytes with mild fibrosis, whereas her lymph nodes lacke...