Cortisol and development of depression in adolescence and young adulthood – a systematic review and meta-analysis

• Published in: Psychoneuroendocrinology Vol. 136; p. 105625
• Main Authors: Zajkowska, Zuzanna, Gullett, Nancy, Walsh, Annabel, Zonca, Valentina, Pedersen, Gloria A., Souza, Laila, Kieling, Christian, Fisher, Helen L., Kohrt, Brandon A., Mondelli, Valeria
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2022; Pergamon Press
• Subjects: Adolescence; Adolescent; Adult; Child; Cortisol; Cross-Sectional Studies; Depression; Depressive Disorder, Major; HPA axis; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Major depressive disorder; Pituitary-Adrenal System; Stress; Young Adult; Adolescence; Depression; Cortisol; HPA axis; Stress; Major depressive disorder

Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been implicated in the development of major depressive disorder (MDD) in adulthood. Less work has focused on the role of the HPA axis in depression in adolescence and young adulthood globally. The aim of this study was to conduct a s...