Identifying chemogenetic interactions from CRISPR screens with drugZ - Colic, Medina; Wang, Gang; Zimmermann, Michal; Mascall, Keith; McLaughlin, Megan; Bertolet, Lori; Lenoir, W. Frank; Moffat, Jason; Angers, Stephane; Durocher, Daniel; Hart, Traver (Genome medicine, 2019)
Keywords: Algorithms; Analysis; Anopheles; Cells (Biology); Chemogenetic interactions; Clustered Regularly Interspaced Short Palindromic Repeats; Computer programs; Criminal investigation; CRISPR; CRISPR screens; CRISPR-Cas Systems; Deoxyribonucleic acid; DNA; DNA damage; DNA repair; Drug Discovery - methods; Drug efficacy; Drug interactions; Drug resistance; Gene mutation; Genes; Genetic Predisposition to Disease; Genomes; Genomics; Humans; Hypothesis testing; Mutation; Novels; Open source software; Pharmacogenetics - methods; Pharmacogenomic Variants; Poly(ADP-ribose) polymerase; Software; Standard deviation; Synthetic lethality; Temozolomide; Tumor suppressor genes; Tumors; Canada; CRISPR screens; Synthetic lethality; Drug resistance; Chemogenetic interactions