Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms TCF7L2 as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk - Groves, Christopher J.; Zeggini, Eleftheria; Minton, Jayne; Frayling, Timothy M.; Weedon, Michael N.; Rayner, Nigel W.; Hitman, Graham A.; Walker, Mark; Wiltshire, Steven; Hattersley, Andrew T.; McCarthy, Mark I. (Diabetes (New York, N.Y.), 2006)
Keywords: Adult; Aged; Analysis; Biological and medical sciences; Chromosomes; Diabetes; Diabetes Mellitus, Type 2 - genetics; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Gene Frequency; Genetic aspects; Genetic Predisposition to Disease; Genetic susceptibility; Genetics, Population; Genomes; Genotype; Genotype & phenotype; Humans; Linkage Disequilibrium; Male; Medical sciences; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; TCF Transcription Factors - genetics; Transcription Factor 7-Like 2 Protein; Transcription factors; Type 2 diabetes; United Kingdom; United Kingdom; United Kingdom--UK; Endocrinopathy; Type 2 diabetes; Human; Sensitivity; Association; Gene; Risk factor; Metabolic diseases; Replication