Survival and ocular preservation in a long-term cohort of Japanese patients with retinoblastoma

• Published in: BMC pediatrics Vol. 20; no. 1; p. 37
• Main Authors: Ueda, Tamaki, Koga, Yuhki, Yoshikawa, Hiroshi, Tanabe, Mika, Yamana, Kanako, Oba, Utako, Nakashima, Kentaro, Ono, Hiroaki, Ichimura, Takuya, Hasegawa, Shunji, Kato, Wakako, Kobayashi, Tetsuko, Nakayama, Hideki, Sakai, Yasunari, Yoshitake, Tadamasa, Ohga, Saiji, Oda, Yoshinao, Suzuki, Shigenobu, Sonoda, Koh-Hei, Ohga, Shouichi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.01.2020; BioMed Central; BMC
• Subjects: Adjuvant chemotherapy; Blindness; Bone cancer; Cancer; Cancer predisposition; Cancer therapies; Cancer treatment; Care and treatment; Chemotherapy; Demographic aspects; Disease; Diseases; Family medical history; Genes; Genetic research; Hospitals; Infants; Laser-therapy; Lymphomas; Medical personnel; Medical research; Metastasis; Mortality; Mutation; Osteosarcoma; Patient outcomes; Patients; Radiation therapy; Radiotherapy; RB1 gene; Retina; Retinoblastoma; Sarcoma; Software; Tumors; Japan; RB1 gene; Chemotherapy; Cancer predisposition; Radiotherapy; Laser-therapy; Blindness

Retinoblastoma is an ocular tumor in infants with cancer predisposition. Treatment of the rare tumor needs to be optimized for ocular preserved survival without second primary malignancy (SPM). We studied the outcomes of all patients with retinoblastoma at a tertiary center in 1984-2016, when preser...