Molecular pattern of lncRNAs in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long...

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Published inJournal of experimental & clinical cancer research Vol. 38; no. 1; pp. 198 - 15
Main Authors Mai, Haoming, Zhou, Bin, Liu, Li, Yang, Fu, Conran, Carly, Ji, Yuan, Hou, Jinlin, Jiang, Deke
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 16.05.2019
BioMed Central
BMC
Subjects
Binding sites
Classification
Deoxyribonucleic acid
DNA
Gene expression
Genomes
Hepatocellular carcinoma
Hepatology
Liver cancer
lncRNA
Medical prognosis
Molecular pattern
Physiology
Polymorphism
Prostate cancer
Proteins
Regulation of biological processes
Review
RNA polymerase
Well-characterized mechanism
Hepatocellular carcinoma
lncRNA
Molecular pattern
Well-characterized mechanism
Regulation of biological processes
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Abstract Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models.
AbstractList Abstract Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models.
Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models.
Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models.Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models.
ArticleNumber 198
Audience Academic
Author Zhou, Bin
Liu, Li
Conran, Carly
Mai, Haoming
Hou, Jinlin
Ji, Yuan
Yang, Fu
Jiang, Deke
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Issue 1
Keywords Hepatocellular carcinoma
lncRNA
Molecular pattern
Well-characterized mechanism
Regulation of biological processes
Language English
License Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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Snippet Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and...
Abstract Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation...
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SubjectTerms Binding sites
Classification
Deoxyribonucleic acid
DNA
Gene expression
Genomes
Hepatocellular carcinoma
Hepatology
Liver cancer
lncRNA
Medical prognosis
Molecular pattern
Physiology
Polymorphism
Prostate cancer
Proteins
Regulation of biological processes
Review
RNA polymerase
Well-characterized mechanism
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Title Molecular pattern of lncRNAs in hepatocellular carcinoma
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https://pubmed.ncbi.nlm.nih.gov/PMC6524221
https://doaj.org/article/15315106318642dfbbd7fdb042007baa
Volume 38
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