Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis

• Published in: Cancer biology & therapy Vol. 10; no. 5; pp. 438 - 447
• Main Authors: Hariri, Lida P., Liebmann, Erica R., Marion, Samuel L., Hoyer, Patricia B., Davis, John R., Brewer, Molly A., Barton, Jennifer K.
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.09.2010; Landes Bioscience
• Subjects: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding; Biology; Bioscience; Calcium; Cancer; Cell; Cycle; Cyclohexenes; Disease Models, Animal; Female; Landes; Lasers; Organogenesis; Ovarian Neoplasms - chemically induced; Ovarian Neoplasms - diagnosis; Ovarian Neoplasms - pathology; Ovary - pathology; Primary Ovarian Insufficiency - etiology; Proteins; Rats; Rats, Inbred F344; Research Paper; Sex Cord-Gonadal Stromal Tumors - diagnosis; Spectrometry, Fluorescence - methods; Tomography, Optical Coherence - methods; Vinyl Compounds

Determining if an ovarian mass is benign or malignant is an ongoing clinical challenge. The development of reliable animal models provides means to evaluate new diagnostic tools to more accurately determine if an ovary has benign or malignant features. Although sex cord-stromal tumors (SCST) account...