Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins

• Published in: Mammalian genome Vol. 21; no. 9-10; pp. 427 - 441
• Main Authors: Holmes, Roger S, Wright, Matthew W, Laulederkind, Stanley J. F, Cox, Laura A, Hosokawa, Masakiyo, Imai, Teruko, Ishibashi, Shun, Lehner, Richard, Miyazaki, Masao, Perkins, Everett J, Potter, Phillip M, Redinbo, Matthew R, Robert, Jacques, Satoh, Tetsuo, Yamashita, Tetsuro, Yan, Bingfan, Yokoi, Tsuyoshi, Zechner, Rudolf, Maltais, Lois J
• Format: Journal Article
• Language: English
• Published: New York New York : Springer-Verlag 01.10.2010; Springer-Verlag; Springer Nature B.V
• Subjects: Amino Acid Sequence; Animal Genetics and Genomics; Animals; Biomedical and Life Sciences; Carboxylesterase - genetics; Cell Biology; Genes; Human Genetics; Humans; Life Sciences; Mice; Multigene Family; Protein Isoforms - genetics; Pseudogenes; Rats; Sequence Homology; Terminology as Topic; Side Door; Transcript Isoforms; Cholesteryl Ester Hydrolase; Homolog Gene Family; Cholesteryl Ester Hydrolase Activity

Mammalian carboxylesterase (CES or Ces) genes encode enzymes that participate in xenobiotic, drug, and lipid metabolism in the body and are members of at least five gene families. Tandem duplications have added more genes for some families, particularly for mouse and rat genomes, which has caused co...