Rapid and Sensitive Identification of Glycoprotein H Genotypes in Clinical Human Cytomegalovirus Samples

• Published in: Japanese Journal of Infectious Diseases Vol. 68; no. 2; pp. 135 - 137
• Main Authors: Li, Wei, Tao, Ran, Zhang, Xiao, Shu, Qiang, Gao, Hui-Hui, Shang, Shi-Qiang, Peng, Zhao-Yang, Li, Hua-Mei
• Format: Journal Article
• Language: English
• Published: Japan National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee 2015
• Subjects: Child; Child, Preschool; China; Cytomegalovirus - classification; Cytomegalovirus - genetics; Cytomegalovirus - isolation & purification; Cytomegalovirus Infections - virology; DNA Primers - genetics; Genotype; Genotyping Techniques - methods; gH genotype; human cytomegalovirus; Humans; Oligonucleotide Probes - genetics; real-time PCR; Real-Time Polymerase Chain Reaction - methods; Sensitivity and Specificity; Time Factors; Urine - virology; Viral Envelope Proteins - genetics; China

Human cytomegalovirus (HCMV) is a common pathogen that causes persistent infections in immune deficient patients and results in significant morbidity and mortality, particularly among transplant recipients and children. Different HCMV glycoprotein H (gH) genotypes may cause different diseases and af...