Plant-specific cochaperone SSR1 affects root elongation by modulating the mitochondrial iron-sulfur cluster assembly machinery

• Published in: PLoS genetics Vol. 21; no. 2; p. e1011597
• Main Authors: Feng, Xuanjun, Hu, Yue, Xie, Tao, Han, Huiling, Bonea, Diana, Zeng, Lijuan, Liu, Jie, Ying, Wenhan, Mu, Bona, Cai, Yuanyuan, Zhang, Min, Lu, Yanli, Zhao, Rongmin, Hua, Xuejun
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 05.02.2025; Public Library of Science (PLoS)
• Subjects: Amino acids; Arabidopsis - genetics; Arabidopsis - growth & development; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Biology and Life Sciences; Gene Expression Regulation, Plant; Genetic aspects; Iron - metabolism; Iron in the body; Iron proteins; Iron-Sulfur Proteins - genetics; Iron-Sulfur Proteins - metabolism; Medicine and Health Sciences; Mitochondria; Mitochondria - genetics; Mitochondria - metabolism; Mitochondrial Proteins - genetics; Mitochondrial Proteins - metabolism; Molecular chaperones; Molecular Chaperones - genetics; Molecular Chaperones - metabolism; Mutation; Physiological aspects; Plant Roots - genetics; Plant Roots - growth & development; Plant Roots - metabolism; Research and Analysis Methods; Roots (Botany); Sulfur; Sulfur - metabolism; Sulfur compounds; China

To elucidate the molecular function of SHORT AND SWOLLEN ROOT1 ( SSR1 ), we screened for su ppressors of the s sr1-2 ( sus ) was performed and identified over a dozen candidates with varying degrees of root growth restoration. Among these, the two most effective suppressors, sus1 and sus2 , resulted...