Impaired glycemia increases disease progression in mild cognitive impairment

• Published in: Neurobiology of aging Vol. 35; no. 3; pp. 585 - 589
• Main Authors: Morris, Jill K., Vidoni, Eric D., Honea, Robyn A., Burns, Jeffrey M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2014
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - diagnosis; Alzheimer Disease - etiology; Alzheimer Disease - pathology; Alzheimer Disease - psychology; Alzheimer's disease; Brain - diagnostic imaging; Brain - pathology; Cognition; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - etiology; Cognitive Dysfunction - pathology; Cognitive Dysfunction - psychology; Dementia; Diabetes; Disease Progression; Female; Humans; Hyperglycemia; Hyperglycemia - complications; Insulin resistance; Internal Medicine; Male; Neurology; Radionuclide Imaging; Risk Factors; Insulin resistance; Hyperglycemia; Diabetes; Alzheimer's disease; Dementia

Insulin resistance and type 2 diabetes are associated with cognitive decline and increased risk for Alzheimer's disease (AD). Relatively few studies have assessed the impact of metabolic dysfunction on conversion to AD in mild cognitive impairment (MCI), and it is unclear whether glycemic statu...