Neuromodulatory Regulation of Behavioral Individuality in Zebrafish

• Published in: Neuron (Cambridge, Mass.) Vol. 91; no. 3; pp. 587 - 601
• Main Authors: Pantoja, Carlos, Hoagland, Adam, Carroll, Elizabeth C., Karalis, Vasiliki, Conner, Alden, Isacoff, Ehud Y.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 03.08.2016; Elsevier Limited
• Subjects: Acoustic Stimulation; Animal behavior; Animals; Animals, Genetically Modified; Apomorphine - pharmacology; Danio rerio; Dorsal Raphe Nucleus - cytology; Dorsal Raphe Nucleus - drug effects; Dorsal Raphe Nucleus - metabolism; Dorsal Raphe Nucleus - physiology; Habituation, Psychophysiologic - drug effects; Habituation, Psychophysiologic - physiology; Individuality; Neurons; Quipazine - pharmacology; Reflex, Startle - drug effects; Reflex, Startle - physiology; Rhodopsin - biosynthesis; Rhodopsin - genetics; Serotonergic Neurons - drug effects; Serotonergic Neurons - metabolism; Serotonergic Neurons - physiology; Serotonin; Serotonin - metabolism; Zebrafish; Zebrafish - physiology

Inter-individual behavioral variation is thought to increase fitness and aid adaptation to environmental change, but the underlying mechanisms are poorly understood. We find that variation between individuals in neuromodulatory input contributes to individuality in short-term habituation of the zebr...