Demographic and clinical correlates of acute and convalescent SARS-CoV-2 infection among patients of a U.S. emergency department
Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED...
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| Published in | The American journal of emergency medicine Vol. 48; pp. 261 - 268 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.10.2021
Elsevier Limited Published by Elsevier Inc |
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| Online Access | Get full text |
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| Abstract | Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED in Baltimore City.
We tested remnant blood samples from 3255 unique ED patients, collected between March 16th and May 31st 2020 for SARS-CoV-2 Ab. PCR for acute SARS-CoV-2 infection from nasopharyngeal swabs was obtained on any patients based on clinical suspicion. Hospital records were abstracted and factors associated with SARS-CoV-2 infection were assessed.
Of 3255 ED patients, 8.2% (95%CI: 7.3%, 9.2%) individuals had evidence of SARS-CoV-2 infection; 155 PCR+, 78 Ab+, and 35 who were both PCR+ and Ab+. Prevalence of disease increased throughout the study period, ranging from 3.2% (95%CI: 1.8%, 5.2%) PCR+ and 0.6% (95%CI: 0.1%, 1.8%) Ab+ in March, to 6.2% (95%CI: 5.1%, 7.4%) PCR+ and 4.2% (95%CI: 3.3%, 5.3%) Ab+ in May. The highest SARS-CoV-2 prevalence was found in Hispanic individuals who made up 8.4% (95%CI: 7.4%, 9.4%) of individuals screened, but 35% (95%CI: 29%, 41%) of infections (PCR and/or Ab+). Demographic and clinical factors independently associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever. Factors independently associated with convalescent infection were Hispanic ethnicity and low oxygen saturation.
The burden of COVID-19 in Baltimore City increased dramatically over the 11-week study period and was disproportionately higher among Hispanic individuals. ED-based surveillance methods are important for identifying both acute and convalescent SARS-CoV-2 infections and provides important information regarding demographic and clinical correlates of disease in the local community. |
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| AbstractList | Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED in Baltimore City.
We tested remnant blood samples from 3255 unique ED patients, collected between March 16th and May 31st 2020 for SARS-CoV-2 Ab. PCR for acute SARS-CoV-2 infection from nasopharyngeal swabs was obtained on any patients based on clinical suspicion. Hospital records were abstracted and factors associated with SARS-CoV-2 infection were assessed.
Of 3255 ED patients, 8.2% (95%CI: 7.3%, 9.2%) individuals had evidence of SARS-CoV-2 infection; 155 PCR+, 78 Ab+, and 35 who were both PCR+ and Ab+. Prevalence of disease increased throughout the study period, ranging from 3.2% (95%CI: 1.8%, 5.2%) PCR+ and 0.6% (95%CI: 0.1%, 1.8%) Ab+ in March, to 6.2% (95%CI: 5.1%, 7.4%) PCR+ and 4.2% (95%CI: 3.3%, 5.3%) Ab+ in May. The highest SARS-CoV-2 prevalence was found in Hispanic individuals who made up 8.4% (95%CI: 7.4%, 9.4%) of individuals screened, but 35% (95%CI: 29%, 41%) of infections (PCR and/or Ab+). Demographic and clinical factors independently associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever. Factors independently associated with convalescent infection were Hispanic ethnicity and low oxygen saturation.
The burden of COVID-19 in Baltimore City increased dramatically over the 11-week study period and was disproportionately higher among Hispanic individuals. ED-based surveillance methods are important for identifying both acute and convalescent SARS-CoV-2 infections and provides important information regarding demographic and clinical correlates of disease in the local community. Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED in Baltimore City.BACKGROUNDEmergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED in Baltimore City.We tested remnant blood samples from 3255 unique ED patients, collected between March 16th and May 31st 2020 for SARS-CoV-2 Ab. PCR for acute SARS-CoV-2 infection from nasopharyngeal swabs was obtained on any patients based on clinical suspicion. Hospital records were abstracted and factors associated with SARS-CoV-2 infection were assessed.METHODSWe tested remnant blood samples from 3255 unique ED patients, collected between March 16th and May 31st 2020 for SARS-CoV-2 Ab. PCR for acute SARS-CoV-2 infection from nasopharyngeal swabs was obtained on any patients based on clinical suspicion. Hospital records were abstracted and factors associated with SARS-CoV-2 infection were assessed.Of 3255 ED patients, 8.2% (95%CI: 7.3%, 9.2%) individuals had evidence of SARS-CoV-2 infection; 155 PCR+, 78 Ab+, and 35 who were both PCR+ and Ab+. Prevalence of disease increased throughout the study period, ranging from 3.2% (95%CI: 1.8%, 5.2%) PCR+ and 0.6% (95%CI: 0.1%, 1.8%) Ab+ in March, to 6.2% (95%CI: 5.1%, 7.4%) PCR+ and 4.2% (95%CI: 3.3%, 5.3%) Ab+ in May. The highest SARS-CoV-2 prevalence was found in Hispanic individuals who made up 8.4% (95%CI: 7.4%, 9.4%) of individuals screened, but 35% (95%CI: 29%, 41%) of infections (PCR and/or Ab+). Demographic and clinical factors independently associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever. Factors independently associated with convalescent infection were Hispanic ethnicity and low oxygen saturation.RESULTSOf 3255 ED patients, 8.2% (95%CI: 7.3%, 9.2%) individuals had evidence of SARS-CoV-2 infection; 155 PCR+, 78 Ab+, and 35 who were both PCR+ and Ab+. Prevalence of disease increased throughout the study period, ranging from 3.2% (95%CI: 1.8%, 5.2%) PCR+ and 0.6% (95%CI: 0.1%, 1.8%) Ab+ in March, to 6.2% (95%CI: 5.1%, 7.4%) PCR+ and 4.2% (95%CI: 3.3%, 5.3%) Ab+ in May. The highest SARS-CoV-2 prevalence was found in Hispanic individuals who made up 8.4% (95%CI: 7.4%, 9.4%) of individuals screened, but 35% (95%CI: 29%, 41%) of infections (PCR and/or Ab+). Demographic and clinical factors independently associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever. Factors independently associated with convalescent infection were Hispanic ethnicity and low oxygen saturation.The burden of COVID-19 in Baltimore City increased dramatically over the 11-week study period and was disproportionately higher among Hispanic individuals. ED-based surveillance methods are important for identifying both acute and convalescent SARS-CoV-2 infections and provides important information regarding demographic and clinical correlates of disease in the local community.CONCLUSIONSThe burden of COVID-19 in Baltimore City increased dramatically over the 11-week study period and was disproportionately higher among Hispanic individuals. ED-based surveillance methods are important for identifying both acute and convalescent SARS-CoV-2 infections and provides important information regarding demographic and clinical correlates of disease in the local community. AbstractBackgroundEmergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED in Baltimore City. MethodsWe tested remnant blood samples from 3255 unique ED patients, collected between March 16th and May 31st 2020 for SARS-CoV-2 Ab. PCR for acute SARS-CoV-2 infection from nasopharyngeal swabs was obtained on any patients based on clinical suspicion. Hospital records were abstracted and factors associated with SARS-CoV-2 infection were assessed. ResultsOf 3255 ED patients, 8.2% (95%CI: 7.3%, 9.2%) individuals had evidence of SARS-CoV-2 infection; 155 PCR+, 78 Ab+, and 35 who were both PCR+ and Ab+. Prevalence of disease increased throughout the study period, ranging from 3.2% (95%CI: 1.8%, 5.2%) PCR+ and 0.6% (95%CI: 0.1%, 1.8%) Ab+ in March, to 6.2% (95%CI: 5.1%, 7.4%) PCR+ and 4.2% (95%CI: 3.3%, 5.3%) Ab+ in May. The highest SARS-CoV-2 prevalence was found in Hispanic individuals who made up 8.4% (95%CI: 7.4%, 9.4%) of individuals screened, but 35% (95%CI: 29%, 41%) of infections (PCR and/or Ab+). Demographic and clinical factors independently associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever. Factors independently associated with convalescent infection were Hispanic ethnicity and low oxygen saturation. ConclusionsThe burden of COVID-19 in Baltimore City increased dramatically over the 11-week study period and was disproportionately higher among Hispanic individuals. ED-based surveillance methods are important for identifying both acute and convalescent SARS-CoV-2 infections and provides important information regarding demographic and clinical correlates of disease in the local community. BackgroundEmergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the earliest phase of the pandemic among patients in an urban ED in Baltimore City.MethodsWe tested remnant blood samples from 3255 unique ED patients, collected between March 16th and May 31st 2020 for SARS-CoV-2 Ab. PCR for acute SARS-CoV-2 infection from nasopharyngeal swabs was obtained on any patients based on clinical suspicion. Hospital records were abstracted and factors associated with SARS-CoV-2 infection were assessed.ResultsOf 3255 ED patients, 8.2% (95%CI: 7.3%, 9.2%) individuals had evidence of SARS-CoV-2 infection; 155 PCR+, 78 Ab+, and 35 who were both PCR+ and Ab+. Prevalence of disease increased throughout the study period, ranging from 3.2% (95%CI: 1.8%, 5.2%) PCR+ and 0.6% (95%CI: 0.1%, 1.8%) Ab+ in March, to 6.2% (95%CI: 5.1%, 7.4%) PCR+ and 4.2% (95%CI: 3.3%, 5.3%) Ab+ in May. The highest SARS-CoV-2 prevalence was found in Hispanic individuals who made up 8.4% (95%CI: 7.4%, 9.4%) of individuals screened, but 35% (95%CI: 29%, 41%) of infections (PCR and/or Ab+). Demographic and clinical factors independently associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever. Factors independently associated with convalescent infection were Hispanic ethnicity and low oxygen saturation.ConclusionsThe burden of COVID-19 in Baltimore City increased dramatically over the 11-week study period and was disproportionately higher among Hispanic individuals. ED-based surveillance methods are important for identifying both acute and convalescent SARS-CoV-2 infections and provides important information regarding demographic and clinical correlates of disease in the local community. |
| Author | Wang, Richard Lake, Isabel V. Patel, Eshan U. Tobian, Aaron A.R. Dashler, Gaby Rothman, Richard E. Kickler, Thomas Laeyendecker, Oliver Miller, Jernelle Kirby, Charles S. Reineck, Sarah Clarke, William Quinn, Thomas C. Eby, Yolanda J. Schmidt, Haley A. Klock, Ethan Youbi, Mehdi Fernandez, Reinaldo E. Anderson, Danna Hurley, Jennifer Hsieh, Yu-Hsiang Ricketts, Erin Khan, Momina Keruly, Morgan Knaub, Ross Baker, Owen R. Kelen, Gabor D. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34015609$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.7326/M20-5661 10.1056/NEJMoa2001017 10.15585/mmwr.mm7015e3 10.15585/mmwr.mm7012e1 10.3201/eid2612.203764 10.1128/JCM.02020-20 10.1136/bmjopen-2020-039849 10.1001/jama.2020.11374 10.1001/jama.1987.03390190087025 10.1093/cid/ciw074 10.1128/JCM.02257-20 10.1016/S0140-6736(20)32009-2 10.1056/NEJMoa2026116 10.1111/acem.14261 10.1126/sciimmunol.abc6347 10.1038/d41586-020-02598-6 10.7326/M20-1495 10.1001/jamainternmed.2020.4130 10.1371/journal.pmed.1003379 10.3201/eid2609.201840 10.15585/mmwr.mm6935e2 10.1172/JCI142004 10.1016/j.jcv.2016.05.003 10.1001/jama.2020.17709 10.1056/NEJMp2024897 10.1001/jama.2020.14765 10.1371/journal.pone.0000489 10.1001/jama.2020.8279 |
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| Contributor | Wang, Richard Anderson, Danna Hurley, Jennifer Schmidt, Haley A Lake, Isabel V Eby, Yolanda J Ricketts, Erin Khan, Momina Keruly, Morgan Knaub, Ross Miller, Jernelle Baker, Owen R Reineck, Sarah Kirby, Charles S Klock, Ethan Youbi, Mehdi |
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| Copyright | 2021 Copyright © 2021. Published by Elsevier Inc. Copyright Elsevier Limited Oct 2021 2021 Published by Elsevier Inc. 2021 |
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| Keywords | SARS-CoV-2 infection Emergency department Clinical correlates Surveillance Demographic correlates Prevalence of SARS-CoV-2 antibody |
| Language | English |
| License | Copyright © 2021. Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Laeyendecker and Hsieh contributed equally to this manuscript and should be considered co‐first authors. |
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| References | Patel, Bloch, Clarke (bb0025) 2021; 59 Bryant, Azman, Ferrari (bb0035) 2020; 5 Centers for Disease Control and Prevention (CDC) (bb0155) 2021 Hsieh, Rothman, Laeyendecker (bb0080) 2016; 62 Conklin, Martin, Manabe (bb0085) 2021; 59 Klein, Pekosz, Park (bb0020) 2020; 130 Moscola, Sembajwe, Jarrett (bb0040) 2020; 324 Sampath, Russell, Massire (bb0070) 2007; 2 Page, Flores-Miller (bb0120) 2021; 384 Sood, Simon, Ebner (bb0130) 2020; 323 Self, Tenforde, Stubblefield (bb0050) 2020; 69 United States Census Bureau. US Census Bureau American Community Survey (bb0095) 2018 World Health Organization (bb0010) 2020 Rubin (bb0145) 2020 Sep; 324 Hughes, Wang, Grossman (bb0150) 2021; 70 United States Census Bureau (bb0090) 2021 Patel, Laeyendecker, Hsieh, Rothman, Kelen, Quinn (bb0065) 2016; 80 Vahidy, Nicolas, Meeks (bb0110) 2020; 10 Marshall (bb0140) 2020; 585 Waxman, Moschella, Duber (bb0165) 2021 Apr Havers, Reed, Lim (bb0125) 2020 Jul Akinbami, Vuong, Petersen (bb0045) 2020; 26 Chopra, Flanders, O’Malley, Malani, Prescott (bb0135) 2021; 174 Smith, DeVies, Caruso (bb0160) 2021; 70 Anand, Montez-Rath, Han (bb0055) 2020; 396 Baker, Kelen, Sivertson, Quinn (bb0060) 1987; 257 Rentsch, Kidwai-Khan, Tate (bb0105) 2020; 17 Zhu, Zhang, Wang (bb0005) 2020; 382 Clapham, Hay, Routledge (bb0030) 2020; 26 Martinez, Hinson, Klein (bb0115) 2020; 324 Misa, Perez, Basham (bb0075) 2020 Sep Fan, Dominitz, Eastment (bb0100) 2020 Oct Gudbjartsson, Norddahl, Melsted (bb0175) 2020; 383 Kucirka, Lauer, Laeyendecker, Boon (bb0180) 2020; 173 Gronvall, Connell, Kobokovich (bb0015) 2020 April Martinez (10.1016/j.ajem.2021.04.081_bb0115) 2020; 324 Hughes (10.1016/j.ajem.2021.04.081_bb0150) 2021; 70 Marshall (10.1016/j.ajem.2021.04.081_bb0140) 2020; 585 Kucirka (10.1016/j.ajem.2021.04.081_bb0180) 2020; 173 Hsieh (10.1016/j.ajem.2021.04.081_bb0080) 2016; 62 Bryant (10.1016/j.ajem.2021.04.081_bb0035) 2020; 5 Smith (10.1016/j.ajem.2021.04.081_bb0160) 2021; 70 Centers for Disease Control and Prevention (CDC) (10.1016/j.ajem.2021.04.081_bb0155) Havers (10.1016/j.ajem.2021.04.081_bb0125) 2020 United States Census Bureau. US Census Bureau American Community Survey (10.1016/j.ajem.2021.04.081_bb0095) Gronvall (10.1016/j.ajem.2021.04.081_bb0015) Patel (10.1016/j.ajem.2021.04.081_bb0025) 2021; 59 Rentsch (10.1016/j.ajem.2021.04.081_bb0105) 2020; 17 Gudbjartsson (10.1016/j.ajem.2021.04.081_bb0175) 2020; 383 Misa (10.1016/j.ajem.2021.04.081_bb0075) 2020 Sood (10.1016/j.ajem.2021.04.081_bb0130) 2020; 323 Vahidy (10.1016/j.ajem.2021.04.081_bb0110) 2020; 10 Chopra (10.1016/j.ajem.2021.04.081_bb0135) 2021; 174 Clapham (10.1016/j.ajem.2021.04.081_bb0030) 2020; 26 Page (10.1016/j.ajem.2021.04.081_bb0120) 2021; 384 Anand (10.1016/j.ajem.2021.04.081_bb0055) 2020; 396 Conklin (10.1016/j.ajem.2021.04.081_bb0085) 2021; 59 Fan (10.1016/j.ajem.2021.04.081_bb0100) 2020 World Health Organization (10.1016/j.ajem.2021.04.081_bb0010) Waxman (10.1016/j.ajem.2021.04.081_bb0165) 2021 Baker (10.1016/j.ajem.2021.04.081_bb0060) 1987; 257 United States Census Bureau (10.1016/j.ajem.2021.04.081_bb0090) Self (10.1016/j.ajem.2021.04.081_bb0050) 2020; 69 Rubin (10.1016/j.ajem.2021.04.081_bb0145) 2020; 324 Patel (10.1016/j.ajem.2021.04.081_bb0065) 2016; 80 Klein (10.1016/j.ajem.2021.04.081_bb0020) 2020; 130 Zhu (10.1016/j.ajem.2021.04.081_bb0005) 2020; 382 Akinbami (10.1016/j.ajem.2021.04.081_bb0045) 2020; 26 Moscola (10.1016/j.ajem.2021.04.081_bb0040) 2020; 324 Sampath (10.1016/j.ajem.2021.04.081_bb0070) 2007; 2 |
| References_xml | – volume: 26 start-page: 2863 year: 2020 end-page: 2871 ident: bb0045 article-title: SARS-CoV-2 seroprevalence among healthcare, first response, and public safety personnel, detroit metropolitan area, Michigan, USA, May–June 2020 publication-title: Emerg Infect Dis – volume: 324 start-page: 893 year: 2020 end-page: 895 ident: bb0040 article-title: Prevalence of SARS-CoV-2 antibodies in health care personnel in the New York City area publication-title: JAMA – volume: 324 start-page: 392 year: 2020 end-page: 395 ident: bb0115 article-title: SARS-CoV-2 positivity rate for Latinos in the Baltimore-Washington, DC Region publication-title: JAMA – volume: 2 year: 2007 ident: bb0070 article-title: Global surveillance of emerging Influenza virus genotypes by mass spectrometry publication-title: PLoS One – volume: 323 start-page: 2425 year: 2020 end-page: 2427 ident: bb0130 article-title: Seroprevalence of SARS-CoV-2–specific antibodies among adults in Los Angeles County, California, on April 10–11, 2020 publication-title: JAMA – volume: 324 start-page: 1381 year: 2020 Sep end-page: 1383 ident: bb0145 article-title: As their numbers grow, COVID-19 "Long Haulers" stump experts publication-title: JAMA – volume: 384 start-page: 5 year: 2021 end-page: 7 ident: bb0120 article-title: Lessons we’ve learned - Covid-19 and the undocumented latinx community publication-title: N Engl J Med – year: 2020 Jul ident: bb0125 article-title: Seroprevalence of antibodies to SARS-CoV-2 in 10 sites in the United States, March 23–May 12, 2020 publication-title: JAMA Intern Med – volume: 80 start-page: 93 year: 2016 end-page: 97 ident: bb0065 article-title: Parallel declines in HIV and hepatitis C virus prevalence, but not in herpes simplex virus type 2 infection: a 10-year, serial cross-sectional study in an inner-city emergency department publication-title: J Clin Virol – volume: 59 year: 2021 ident: bb0085 article-title: Evaluation of serological SARS-CoV-2 lateral flow assays for rapid point-of-care testing publication-title: J Clin Microbiol – volume: 62 start-page: 1059 year: 2016 end-page: 1065 ident: bb0080 article-title: Evaluation of the centers for disease control and prevention recommendations for hepatitis C virus testing in an urban emergency department publication-title: Clin Infect Dis – volume: 173 start-page: 262 year: 2020 end-page: 267 ident: bb0180 article-title: Variation in false-negative rate of reverse transcriptase polymerase chain reaction-based SARS-CoV-2 tests by time since exposure publication-title: Ann Intern Med – volume: 10 year: 2020 ident: bb0110 article-title: Racial and ethnic disparities in SARS-CoV-2 pandemic: analysis of a COVID-19 observational registry for a diverse US metropolitan population publication-title: BMJ Open – year: 2018 ident: bb0095 article-title: American Community Survey 5 Year Estimates, Tables B03002, S1701, and B01003 – volume: 26 start-page: 1978 year: 2020 end-page: 1986 ident: bb0030 article-title: Seroepidemiologic study designs for determining SARS-COV-2 transmission and immunity publication-title: Emerg Infect Dis – volume: 585 start-page: 339 year: 2020 end-page: 341 ident: bb0140 article-title: The lasting misery of coronavirus long-haulers publication-title: Nature – volume: 59 year: 2021 ident: bb0025 article-title: Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers publication-title: J Clin Microbiol – volume: 130 start-page: 6141 year: 2020 end-page: 6150 ident: bb0020 article-title: Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population publication-title: J Clin Invest – year: 2021 ident: bb0090 article-title: Zip Code Tabulation Areas (ZCTA) – volume: 174 start-page: 576 year: 2021 end-page: 578 ident: bb0135 article-title: Sixty-day outcomes among patients hospitalized with COVID-19 publication-title: Ann Intern Med – volume: 70 start-page: 566 year: 2021 end-page: 569 ident: bb0160 article-title: Emergency department visits for COVID-19 by race and ethnicity - 13 states, October–December 2020 publication-title: MMWR Morb Mortal Wkly Rep – year: 2021 Apr ident: bb0165 article-title: Emergency department-based COVID-19 vaccination: where do we stand? publication-title: Acad Emerg Med – year: 2020 ident: bb0010 article-title: Timeline: WHO's COVID-19 Response – year: 2020 Sep ident: bb0075 article-title: Racial/ethnic disparities in COVID-19 disease burden & mortality among emergency department patients in a safety net health system publication-title: Am J Emerg Med – volume: 382 start-page: 727 year: 2020 end-page: 733 ident: bb0005 article-title: A novel coronavirus from patients with pneumonia in China, 2019 publication-title: N Engl J Med – year: 2020 April ident: bb0015 article-title: Developing a National Strategy for Serology (Antibody Testing) in the United States – volume: 70 start-page: 431 year: 2021 end-page: 436 ident: bb0150 article-title: County-level COVID-19 vaccination coverage and social vulnerability - United States, December 14, 2020–March 1, 2021 publication-title: MMWR Morb Mortal Wkly Rep – volume: 383 start-page: 1724 year: 2020 end-page: 1734 ident: bb0175 article-title: Humoral immune response to SARS-CoV-2 in Iceland publication-title: N Engl J Med – volume: 5 year: 2020 ident: bb0035 article-title: Serology for SARS-CoV-2: apprehensions, opportunities, and the path forward publication-title: Sci Immunol – volume: 17 year: 2020 ident: bb0105 article-title: Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans: a nationwide cohort study publication-title: PLoS Med – volume: 69 start-page: 1221 year: 2020 end-page: 1226 ident: bb0050 article-title: Seroprevalence of SARS-CoV-2 among frontline health care personnel in a multistate hospital network - 13 academic medical centers, April–June 2020 publication-title: MMWR Morb Mortal Wkly Rep – volume: 257 start-page: 2609 year: 1987 end-page: 2611 ident: bb0060 article-title: Unsuspected human immunodeficiency virus in critically ill emergency patients publication-title: JAMA – volume: 396 start-page: 1335 year: 2020 end-page: 1344 ident: bb0055 article-title: Prevalence of SARS-CoV-2 antibodies in a large nationwide sample of patients on dialysis in the USA: a cross-sectional study publication-title: Lancet – year: 2021 ident: bb0155 article-title: Interim Guidelines for COVID-19 Antibody Testing - Interim Guidelines for COVID-19 Antibody Testing in Clinical and Public Health Settings – year: 2020 Oct ident: bb0100 article-title: Risk factors for testing positive for SARS-CoV-2 in a national us healthcare system publication-title: Clin Infect Dis – volume: 174 start-page: 576 issue: 4 year: 2021 ident: 10.1016/j.ajem.2021.04.081_bb0135 article-title: Sixty-day outcomes among patients hospitalized with COVID-19 publication-title: Ann Intern Med doi: 10.7326/M20-5661 – volume: 382 start-page: 727 issue: 8 year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0005 article-title: A novel coronavirus from patients with pneumonia in China, 2019 publication-title: N Engl J Med doi: 10.1056/NEJMoa2001017 – volume: 70 start-page: 566 issue: 15 year: 2021 ident: 10.1016/j.ajem.2021.04.081_bb0160 article-title: Emergency department visits for COVID-19 by race and ethnicity - 13 states, October–December 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm7015e3 – ident: 10.1016/j.ajem.2021.04.081_bb0010 – year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0075 article-title: Racial/ethnic disparities in COVID-19 disease burden & mortality among emergency department patients in a safety net health system publication-title: Am J Emerg Med – volume: 70 start-page: 431 issue: 12 year: 2021 ident: 10.1016/j.ajem.2021.04.081_bb0150 article-title: County-level COVID-19 vaccination coverage and social vulnerability - United States, December 14, 2020–March 1, 2021 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm7012e1 – ident: 10.1016/j.ajem.2021.04.081_bb0015 – volume: 26 start-page: 2863 issue: 12 year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0045 article-title: SARS-CoV-2 seroprevalence among healthcare, first response, and public safety personnel, detroit metropolitan area, Michigan, USA, May–June 2020 publication-title: Emerg Infect Dis doi: 10.3201/eid2612.203764 – volume: 59 issue: 2 year: 2021 ident: 10.1016/j.ajem.2021.04.081_bb0085 article-title: Evaluation of serological SARS-CoV-2 lateral flow assays for rapid point-of-care testing publication-title: J Clin Microbiol doi: 10.1128/JCM.02020-20 – volume: 10 issue: 8 year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0110 article-title: Racial and ethnic disparities in SARS-CoV-2 pandemic: analysis of a COVID-19 observational registry for a diverse US metropolitan population publication-title: BMJ Open doi: 10.1136/bmjopen-2020-039849 – volume: 324 start-page: 392 issue: 4 year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0115 article-title: SARS-CoV-2 positivity rate for Latinos in the Baltimore-Washington, DC Region publication-title: JAMA doi: 10.1001/jama.2020.11374 – volume: 257 start-page: 2609 issue: 19 year: 1987 ident: 10.1016/j.ajem.2021.04.081_bb0060 article-title: Unsuspected human immunodeficiency virus in critically ill emergency patients publication-title: JAMA doi: 10.1001/jama.1987.03390190087025 – volume: 62 start-page: 1059 issue: 9 year: 2016 ident: 10.1016/j.ajem.2021.04.081_bb0080 article-title: Evaluation of the centers for disease control and prevention recommendations for hepatitis C virus testing in an urban emergency department publication-title: Clin Infect Dis doi: 10.1093/cid/ciw074 – volume: 59 issue: 2 year: 2021 ident: 10.1016/j.ajem.2021.04.081_bb0025 article-title: Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers publication-title: J Clin Microbiol doi: 10.1128/JCM.02257-20 – year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0100 article-title: Risk factors for testing positive for SARS-CoV-2 in a national us healthcare system publication-title: Clin Infect Dis – volume: 396 start-page: 1335 issue: 10259 year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0055 article-title: Prevalence of SARS-CoV-2 antibodies in a large nationwide sample of patients on dialysis in the USA: a cross-sectional study publication-title: Lancet doi: 10.1016/S0140-6736(20)32009-2 – volume: 383 start-page: 1724 issue: 18 year: 2020 ident: 10.1016/j.ajem.2021.04.081_bb0175 article-title: Humoral immune response to SARS-CoV-2 in Iceland publication-title: N Engl J Med doi: 10.1056/NEJMoa2026116 – year: 2021 ident: 10.1016/j.ajem.2021.04.081_bb0165 article-title: Emergency department-based COVID-19 vaccination: where do we stand? publication-title: Acad Emerg 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| Snippet | Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of... AbstractBackgroundEmergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and... BackgroundEmergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal... |
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| SubjectTerms | Acute Disease Adolescent Adult Aged Algorithms Antibodies Asymptomatic Black or African American Clinical correlates Convalescence Coronaviruses Cough COVID-19 COVID-19 - epidemiology COVID-19 - ethnology COVID-19 - physiopathology COVID-19 Nucleic Acid Testing COVID-19 Serological Testing Datasets Demographic correlates Emergency Emergency department Emergency medical care Emergency Service, Hospital Epidemics Estimates Ethnicity Female Fever Hispanic Americans Hispanic or Latino - statistics & numerical data Humans Hypoxia - physiopathology Infections Infectious diseases Laboratories Male Middle Aged Minority & ethnic groups Olfaction Pandemics Patients Prevalence Prevalence of SARS-CoV-2 antibody Public health SARS-CoV-2 SARS-CoV-2 infection Seroepidemiologic Studies Severe acute respiratory syndrome coronavirus 2 Surveillance United States - epidemiology Variables Vital signs White People Young Adult |
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| Title | Demographic and clinical correlates of acute and convalescent SARS-CoV-2 infection among patients of a U.S. emergency department |
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