Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms to prevent telomere shortening. ~85% of cancers circumvent telomeric attrition by re-expressing telomerase, while the remaining ~15% of cancers induce alternative lengthening of telomeres (ALT), which reli...
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Published in | Nature communications Vol. 12; no. 1; pp. 512 - 11 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
21.01.2021
Nature Publishing Group Nature Portfolio |
Subjects | |
Online Access | Get full text |
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