The influence of spaceflight on the astronaut salivary microbiome and the search for a microbiome biomarker for viral reactivation

• Published in: Microbiome Vol. 8; no. 1; pp. 56 - 14
• Main Authors: Urbaniak, Camilla, Lorenzi, Hernan, Thissen, James, Jaing, Crystal, Crucian, Brian, Sams, Clarence, Pierson, Duane, Venkateswaran, Kasthuri, Mehta, Satish
• Format: Journal Article
• Language: English
• Published: England BioMed Central 20.04.2020; BMC
• Subjects: Adult; Astronaut microbiome; Astronauts; Bacteria; Bacteria - classification; Bacteria - isolation & purification; BASIC BIOLOGICAL SCIENCES; Biomarkers; Biomarkers - metabolism; Cardiovascular disease; Colorectal cancer; Cytomegalovirus; Diabetes; Epstein-Barr virus; Herpes simplex; Herpes viruses; Humans; International space station; Male; Microbiomes; Microbiota; Phylogenetics; Polymerase chain reaction; rRNA 16S; Saliva; Saliva - microbiology; Saliva - virology; Salivary microbiome; Space Flight; Spaceflight; Statistical analysis; Stress, Physiological; Varicella; Viral Load; Viral reactivation; Virus Activation; Viruses - isolation & purification; Salivary microbiome; Astronaut microbiome; International space station; Spaceflight; Viral reactivation

Spaceflight impacts astronauts in many ways but little is known on how spaceflight affects the salivary microbiome and the consequences of these changes on astronaut health, such as viral reactivation. In order to understand this, the salivary microbiome was analyzed with 16S rRNA gene amplicon sequ...